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Constructing and Evaluating Digital Twins: An Intelligent Framework for DT Development
The development of Digital Twins (DTs) represents a transformative advance for simulating and optimizing complex systems in a controlled digital space. Despite their potential, the challenge of constructing DTs that accurately replicate and predict the dynamics of real-world systems remains substantial.
Longfei Ma +6 more
openaire +2 more sources
Digital Twin for Neurology: An Introduction to a New Frontier in Healthcare [PDF]
A digital twin (DT) is a virtual representation of a real thing that features two-way interactive links connecting the physical object and its digital twin.
Ashraf, Taniya +2 more
core +1 more source
Research objectives and hypothesis/research questions In this study, there are two theorized foundations: First-the adopting of Digital Twin technology has a positive impact on the financial performance of the case subject company. Second-the differences
Mohamed Boulesnam +3 more
doaj +1 more source
Anatomy-DT: A Cross-Diffusion Digital Twin for Anatomical Evolution
Accurately modeling the spatiotemporal evolution of tumor morphology from baseline imaging is a pre-requisite for developing digital twin frameworks that can simulate disease progression and treatment response. Most existing approaches primarily characterize tumor growth while neglecting the concomitant alterations in adjacent anatomical structures. In
Moinak Bhattacharya +2 more
openaire +2 more sources
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Large language models forecast patient health trajectories enabling digital twins
Generative artificial intelligence is revolutionizing digital twin development, enabling virtual patient representations that predict health trajectories, with large language models (LLMs) showcasing untapped clinical forecasting potential.
Nikita Makarov +6 more
doaj +1 more source
Digital Twin (DT) technology is an essential technology related to the Industry 4.0. In engineering education, it is important that the curricula are kept up-to-date.
Liljaniemi Antti, Paavilainen Heikki
doaj +1 more source
Digital Twin Ecosystems : Potential Stakeholders and Their Requirements [PDF]
Context: As industries are heading for digital transformation through Industry 4.0, the concept of Digital Twin (DT) — a software for digital transformation, has become popular.
Xu, Yueqiang +7 more
core +1 more source
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source

