Results 111 to 120 of about 2,595 (165)
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Clinical use of digitalis glycosides
American Journal of Health-System Pharmacy, 1976The pharmacology of digitalis compounds is reviewed, and the clinical use of the cardiac glycosides is discussed with particular attention to the selection of patients for digitalis therapy and to a study of the usefulness of various methods to monitor digitalis therapy.
Russell R Miller
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2023
Abstract The potential of digitalis glycosides in heart failure therapy has been long known. In the only large placebo-controlled, randomized trial, namely the DIG trial, digoxin had a neutral effect on overall mortality in patients with heart failure with reduced ejection fraction (HFrEF), but led to significantly reduced heart failure ...
Udo Bavendiek, Johann Bauersachs
openaire +1 more source
Abstract The potential of digitalis glycosides in heart failure therapy has been long known. In the only large placebo-controlled, randomized trial, namely the DIG trial, digoxin had a neutral effect on overall mortality in patients with heart failure with reduced ejection fraction (HFrEF), but led to significantly reduced heart failure ...
Udo Bavendiek, Johann Bauersachs
openaire +1 more source
Interference of uzara glycosides in assays of digitalis glycosides
Int. Journal of Clinical Pharmacology and Therapeutics, 2004Presentation of a case report and pharmacokinetic investigation in healthy volunteers on the potential interference between cardiac glycosides and glycosides of Uzara, a herbal antidiarrheal preparation.Pharmacokinetic pilot investigation of apparent digitoxin and digoxin serum concentrations in 4 healthy volunteers after single-dose administration of ...
P A, Thürmann, A, Neff, J, Fleisch
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Mayo Clinic proceedings, 1979
The digitalis glycosides number among the most commonly used cardiovascular drugs. Despite 200 years of investigation, much new information regarding their mechanisms of action and clinical use continues to be developed. Clinicians dispensing these potent drugs need to be aware of thes advances if they are to make the best possible therapeutic ...
J F, Bresnahan, R E, Vlietstra
openaire +1 more source
The digitalis glycosides number among the most commonly used cardiovascular drugs. Despite 200 years of investigation, much new information regarding their mechanisms of action and clinical use continues to be developed. Clinicians dispensing these potent drugs need to be aware of thes advances if they are to make the best possible therapeutic ...
J F, Bresnahan, R E, Vlietstra
openaire +1 more source
Enzymatic Decomposition of Digitalis Glycosides IV
Journal of the American Pharmaceutical Association (Scientific ed.), 1959Using paper chromatographic methods the glycosidic constituents of freshly gathered leaves of Digitalis lanata have been examined before and after exposure to a limited period of enzymatic action. It appears that the original plant does not contain desglucoglycosides in quantities detectable by very sensitive methods, but that after exposure to ...
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Drug Interactions with Digitalis Glycosides
Drugs, 1978The 2 major factors affecting serum levels of the most commonly used cardiac glycoside digoxin, are patient compliance and the physical characteristics of the tablet; the latter is unimportant with the lipid soluble glycosides digitoxin and β-methyldigoxin.
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Determination of the Purity of Digitalis Glycosides
Journal of the American Pharmaceutical Association (Scientific ed.), 1954A procedure is given for determining the amount of impurities resent in digitalis glycosides and some of their preparations based on the fluorescence produced with a solution of propylene glycol and hydrochloric acid.
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