Results 151 to 160 of about 3,015 (202)

Selective inhibition of human erythrocyte Na+/K+ ATPase by cardiac glycosides and by a mammalian digitalis like factor

Life Sciences, 2000
Na+/K(+)ATPase is a transport membrane protein which contains the functional receptor for digitalis compounds, In this work we compare the inhibition curves of Na+/K(+)ATPase measured by the inhibition of Rb-86 uptake in human red blood cells by cardiac ...
Silvana Balzan, Sérgio Ghione, Adriano Martinelli   +2 more
exaly   +2 more sources

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Digitalis glycosides

2023
Abstract The potential of digitalis glycosides in heart failure therapy has been long known. In the only large placebo-controlled, randomized trial, namely the DIG trial, digoxin had a neutral effect on overall mortality in patients with heart failure with reduced ejection fraction (HFrEF), but led to significantly reduced heart failure ...
Udo Bavendiek, Johann Bauersachs
openaire   +1 more source

Digitalis glycosides

N. Tobarran, B.K. Wills
exaly   +2 more sources

Interference of uzara glycosides in assays of digitalis glycosides

Int. Journal of Clinical Pharmacology and Therapeutics, 2004
Presentation of a case report and pharmacokinetic investigation in healthy volunteers on the potential interference between cardiac glycosides and glycosides of Uzara, a herbal antidiarrheal preparation.Pharmacokinetic pilot investigation of apparent digitoxin and digoxin serum concentrations in 4 healthy volunteers after single-dose administration of ...
P A, Thürmann, A, Neff, J, Fleisch
openaire   +2 more sources

Digitalis glycosides.

Mayo Clinic proceedings, 1979
The digitalis glycosides number among the most commonly used cardiovascular drugs. Despite 200 years of investigation, much new information regarding their mechanisms of action and clinical use continues to be developed. Clinicians dispensing these potent drugs need to be aware of thes advances if they are to make the best possible therapeutic ...
J F, Bresnahan, R E, Vlietstra
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Enzymatic Decomposition of Digitalis Glycosides IV

Journal of the American Pharmaceutical Association (Scientific ed.), 1959
Using paper chromatographic methods the glycosidic constituents of freshly gathered leaves of Digitalis lanata have been examined before and after exposure to a limited period of enzymatic action. It appears that the original plant does not contain desglucoglycosides in quantities detectable by very sensitive methods, but that after exposure to ...
openaire   +4 more sources

Drug Interactions with Digitalis Glycosides

Drugs, 1978
The 2 major factors affecting serum levels of the most commonly used cardiac glycoside digoxin, are patient compliance and the physical characteristics of the tablet; the latter is unimportant with the lipid soluble glycosides digitoxin and β-methyldigoxin.
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Determination of the Purity of Digitalis Glycosides

Journal of the American Pharmaceutical Association (Scientific ed.), 1954
A procedure is given for determining the amount of impurities resent in digitalis glycosides and some of their preparations based on the fluorescence produced with a solution of propylene glycol and hydrochloric acid.
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Radioimmunoassay Of Digitalis Glycosides

Acta Clinica Belgica, 1976
F M, Belpaire, M G, Bogaert
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The Clinical Pharmacology of Digitalis Glycosides

The American Journal of The Medical Sciences, 1968
AbstractThe metabolic half-times and excretion rates of labeled cardiac glycosides are related to pharmacologic or therapeutic activity. Digoxin, a short-acting glycoside, is excreted primarily in the urine and has a serum half-time of 34 hours.
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