Results 51 to 60 of about 48,114 (293)
Digitalisation and Democracy [PDF]
, 2021 Digital Infrastructures are playing an increasingly important role in the processes and developments of a democracy. This is because digitalisation expands the options for information, communication and participation.
Deutsche Akademie der Technikwissenschaften +2 more
core +1 more source
Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham +7 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Digitalisation of medicines: artefact, architecture and time [PDF]
BMJ Quality & Safety, 2017 > Digitalization: ‘The encoding of analogue information into a digital format and the possible subsequent reconfigurations of the socio-technical context of production and consumption of the associated products and services’ .1 This edition includes two papers reporting research from a 5-year study of electronic prescribing in English hospitals.2 3 ...
Cornford, T, Lichtner, V
openaire +5 more sources
Investigating disparities in SMEs digitalisation [PDF]
© The Enterprise Research Centre 2024. Research paper and policy briefing.This research investigates disparities in digitalisation among UK Small and Medium-sized Enterprises (SMEs), with a specific focus on variations by gender, ethnicity, region, and ...
Mahmood, Samia +2 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Path2dea survey on digitalisation
, 2023 Path2dea (PAving THe way towards Digitalisation Enabeling Agroecology) first results of a survey on digitalisation presented within the workshop on Digitalisation for sustainable farming organized by the European Policy ...
Herforth-Rahmé, Joelle
core +1 more source