Results 131 to 140 of about 3,700,434 (389)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Concepts, Introspection, and Phenomenal Consciousness: An Information-Theoretical Approach [PDF]

open access: yes, 2001
This essay is a sustained information-theoretic attempt to bring new light on some of the perennial problems in the philosophy of mind surrounding phenomenal consciousness and introspection.
Aydede, Murat, Guven, Guzeldere
core  

Computing Logarithms Digit-by-Digit

open access: yesBRICS Report Series, 2004
In this work, we present an algorithm for computing logarithms of positive real numbers, that bares structural resemblance to the elementary school algorithm of long division. Using this algorithm, we can compute successive digits of a logarithm using a 4-operation pocket calculator.
openaire   +3 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

How can data analytics and employee upskilling foster digital maturity and sustainable practices in SMES? [PDF]

open access: yesProblems and Perspectives in Management
The accelerating pace of digital and environmental transformation presents both opportunities and challenges for small- and medium-sized enterprises (SMEs) across the European Union.
Levente Peter Balint   +3 more
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Spatial variations of runoff thresholds associated with changes in land use over the period 1990-2018 in the Mediterranean side of Andalusia

open access: yesInvestigaciones Geográficas
The runoff threshold is the amount of precipitation that exceeds the infiltration capacity of the soil and from which water begins to flow over the land surface.
Héctor Álvarez-García   +3 more
doaj   +1 more source

Digitalization and Innovation [PDF]

open access: yes
Developments in digital technology offer new opportunities to design new products and services. However, creating such digitalized products and services often creates new problems and challenges to firms that are trying to innovate.
Yoo, Youngjin
core  

Digital Technologies – Digital Culture

open access: yesNordic Journal of Commercial Law, 2010
Nordic Journal of Commercial Law, No. 1 (2010)
openaire   +4 more sources

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