Results 61 to 70 of about 262,727 (287)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
A New Hyperchaotic Image Encryption Algorithm Based on Stochastic Signals
IEEE Access, 2021 Image encryption is often used to protect private images during transmission on a public channel. A high dimensional chaotic map has a greater secret key space, better ergodicity and dynamic property than a low-dimensional chaotic system.
Shuliang Sun, Yongning Guo
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Toward deep assessments: On the possibility of decolonial digital technologies
TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und PraxisConsidering the coloniality of current digital tools and their increasingly massive global social and ecological impacts, we explore the question of what socio-cultural assemblages can contribute to deep civilizational transformations.
Dorian Cavé, Rainer Rehak
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
MachinesThis work proposes a general methodology for the design and experimental validation of dual-arm robotic platforms intended for intelligent manipulation tasks in real-world environments.
Mario Peñacoba-Yagüe +1 more
doaj +1 more source
Digitalization of International Trade [PDF]
, 2019 The question this article addresses is how the WTO supports and deals with digital trade. The article then analyzes how existing WTO agreements have dealt with digital trade.
Malkawi, Bashar H.
core
Digital lifestyle – digital citizenship – digital pedagogy
Opus et Educatio, 2019 „2017 from within the EU the Internet access households ratio has risen to 87%, which is 32% points exceed the ten years ago, 2007 levels. In 2017, 85% of the EU households used broadband network, which is approximately the double of the 2007 ratio.
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Trajectory Tracking Nonlinear Hybrid Control of Automated Guided Vehicles
ComplexityAutomated guided vehicles (AGVs), so necessary in industrial environments, require precise control of trajectory tracking to make accurate stops at logistics stations, such as loading stations, or to pick up or drop off trolleys, pallets, or racks.
Antonio Sánchez-Rodríguez +3 more
doaj +1 more source