Results 61 to 70 of about 87,888 (344)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Problems and opportunities of applying data-& audio-mining techniques to ethnic music [PDF]
, 2006 [TODO] Add abstract ...
Cornelis, Olmo +7 more
core +2 more sources
Digitisation of metal AM for part microstructure and property control
International Journal of Material Forming, 2022 Metal additive manufacturing, which uses a layer-by-layer approach to fabricate parts, has many potential advantages over conventional techniques, including the ability to produced complex geometries, fast new design part production, personalised ...
M. Doğu +7 more
semanticscholar +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Remote Real-Time Collaboration Platform enabled by the Capture, Digitisation and Transfer of Human-Workpiece Interactions [PDF]
, 2015 In this highly globalised manufacturing ecosystem, product design and verification activities, production and inspection processes, and technical support services are spread across global supply chains and customer networks.
Advikolanu, Yohann +5 more
core
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Audiovisual research collections and their preservation [PDF]
, 2008 The basic problem of primary audio and video research materials is clearly shown by the survey: A great and important part of the entire heritage is still outside archival custody in the narrower sense, scattered over many institutions in fairy small ...
Schüller, Dietrich
core
HTS Teologiese Studies/Theological Studies, 2022 indigenous communities in Africa were directly and indirectly affected by colonisation, which led to the loss of individual and community identity. As such, cultural norms and values were lost.
S. L. Kugara, S. Mokgoatšana
semanticscholar +1 more source
Functional Connectivity Linked to Cognitive Recovery After Minor Stroke
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri +7 more
wiley +1 more source