Results 161 to 170 of about 3,653 (213)
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C12-Hydroxylation of Digitoxin
Nature, 1957USING paper chromatographic methods it has been shown that, following digitoxin administration to rats, the urine contains small amounts of unchanged digitoxin together with larger quantities of two cardioactive metabolites previously designated metabolites C and G 1,2. Human urine collected for 12 hr. from normal adults after an oral dose of 1 mgm. of
B T, BROWN, S E, WRIGHT, G T, OKITA
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The effect of digitoxin on the electrocardiogram
American Heart Journal, 1952Abstract This study would indicate that digotixin changes the order of repolarization in a predictable manner though in an unpredictable amount in both normal and abnormal hearts. The changes in S-T and T as well as Q-T c are best explained by acceleration of repolarization in subendocardial muscle, thus abolishing the normal ventricular gradient ...
R E, WESTLAKE +3 more
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Noninteraction of Digitoxin and Quinidine
New England Journal of Medicine, 1980A LARGE and clinically important interaction between digoxin and quinidine is now well documented.1 2 3 4 5 The cardiac glycoside digitoxin is extensively used in clinical practice, but its interaction with quinidine has not been definitively evaluated.6 , 7 In this study, which assessed the pharmacokinetic interaction of digitoxin with quinidine, we ...
H R, Ochs +3 more
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Accidental Digitoxin Poisoning
Archives of Pediatrics & Adolescent Medicine, 1976A healthy 141/2-month-old child ingested 1.5 mg of digitoxin by accident. Digitoxin was wrongly identified as digoxin, the initial electrocardiogram was misinterpreted, and the vomiting was underestimated as an important symptom of toxicity. Symptoms persisted and the patient was hospitalized.
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Journal of the American Pharmaceutical Association (Scientific ed.), 1953
P, DEMOEN, P, JANSSEN
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P, DEMOEN, P, JANSSEN
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