Results 131 to 140 of about 92,853 (340)

Lack of effect of ezogabine/retigabine on the pharmacokinetics of digoxin in healthy individuals: results from a drug–drug interaction study

Clinical Pharmacology: Advances and Applications, 2014
Debra J Tompson,1 Christopher S Crean,2 Mauro Buraglio,1 Thangam Arumugham3 1Clinical Pharmacology Modelling and Simulation, GlaxoSmithKline, Stevenage, Hertfordshire, UK; 2Clinical Pharmacology and Pharmacokinetics, Valeant Pharmaceuticals North America,
Tompson DJ, Crean CS, Buraglio M, Arumugham T   +3 more
doaj  

Predicting the serum digoxin concentrations of infants in the neonatal intensive care unit through an artificial neural network

BMC Pediatrics, 2019
Background Given its narrow therapeutic range, digoxin’s pharmacokinetic parameters in infants are difficult to predict due to variation in birth weight and gestational age, especially for critically ill newborns. There is limited evidence to support the
Shu-Hui Yao, Hsiang-Te Tsai, Wen-Lin Lin, Yu-Chieh Chen, Chiahung Chou, Hsiang-Wen Lin   +5 more
doaj   +1 more source

Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection

mBio, 2016
Chikungunya virus (CHIKV) is a reemerging alphavirus that has caused epidemics of fever, arthralgia, and rash worldwide. There are currently no licensed vaccines or antiviral therapies available for the prevention or treatment of CHIKV disease.
Alison W. Ashbrook, Anthony J. Lentscher, Paula F. Zamora, Laurie A. Silva, Nicholas A. May, Joshua A. Bauer, Thomas E. Morrison, Terence S. Dermody   +7 more
doaj   +1 more source

Some Effects of Digoxin on the Heart and Circulation in Man [PDF]

, 1951
RÉJANE M. HARVEY, M. IRENÉ FERRER, Richard Cathcart, James Alexander   +3 more
openalex   +1 more source

Minimization or withdrawal of oral pharmacotherapy in chronic heart failure patients with improved myocardial function: A systematic review

European Journal of Heart Failure, EarlyView.
This systematic review included seven studies that reported the outcomes of minimization or withdrawal of oral pharmacotherapy in chronic heart failure (HF) patients with improved myocardial function. There is a dearth of existing evidence, which supports only loop diuretic withdrawal and possibly carvedilol monotherapy.
Yuxiang Luo, Wenbin Xiao, Yusuf Z. Sener, Wouter C. Meijers, Robert M.A. van der Boon, Elfatih A. Hasabo, Osama Soliman, Rudolf A. de Boer, Kadir Caliskan   +8 more
wiley   +1 more source

Effects of Acute and Chronic Digoxin Administration in Dogs with Right-Sided Congestive Heart Failure Produced by Pulmonary Artery Constriction [PDF]

, 1955
James O. Davis, David S. Howell, Robert E. Hyatt, ALFKED CASPEU   +3 more
openalex   +1 more source

Inappropriate use of digoxin in patients presenting with digoxin toxicity.

Journal of geriatric cardiology : JGC, 2015
PubMed ID ...
Tatlısu, Mustafa Adem, Özcan, Kazım Serhan, Güngör, Barış, Zengin, Ahmet, Karataş, Mehmet Baran, Nurkalem, Zekeriya   +5 more
openaire   +4 more sources

Finerenone, chronic obstructive pulmonary disease, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status. BMI, body mass index; LVEF, left ventricular ejection fraction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide.
Jawad H. Butt, Pardeep S. Jhund, Alasdair D. Henderson, Brian L. Claggett, Akshay S. Desai, Carolyn S.P. Lam, Katharina Mueller, Markus F. Scheerer, Prabhakar Viswanathan, Michele Senni, Sanjiv J. Shah, Adriaan A. Voors, Faiez Zannad, Bertram Pitt, Muthiah Vaduganathan, Scott D. Solomon, John J.V. McMurray   +16 more
wiley   +1 more source

Retrospective evaluation of patients with elevated digoxin levels at an emergency department

Turkish Journal of Emergency Medicine, 2016
Objectives: We investigated the demographic characteristics, clinical and laboratory findings, treatment strategies and clinical outcomes of patients presenting at emergency department (ED) with digoxin levels at or above 1.2 ng/ml. Materials and methods:
Gulsum Limon, Gurkan Ersoy, Nese Colak Oray, Basak Bayram, Onder Limon   +4 more
doaj  

Sensitivity to propranolol after digoxin intoxication. [PDF]

, 1968
D. A. L. Watt
openalex   +1 more source