Results 161 to 170 of about 92,853 (340)

Propranolol and Digoxin Intoxication [PDF]

, 1968
D. A. L. Watt
openalex   +1 more source

Glial Versus Neuronal Na+/K+‐ATPase in Activity‐Evoked K+ Clearance and Their Sensitivity to Elevated Extracellular K+

Glia, EarlyView.
The glial Na+ pump regulates [K+]o during neuronal activity, and the neuronal version restores [K+]o to baseline. Spreading depression‐related rise of K+ does not cause SD propagation via suppression of Na+/K+‐ATPase or glutamate transport. ABSTRACT Neuronal activity in the central nervous system is associated with a [K+]o transient that is swiftly ...
Brian Skriver Nielsen, Brian Roland Larsen, Afnan Bilal Ghazal, Adriana Katz, K. C. Brennan, Steven J. D. Karlish, Nanna MacAulay   +6 more
wiley   +1 more source

Antidote Stocking at Hospitals in North Palestine [PDF]

, 2007
Objective: The purpose of this study was to determine the availability and adequacy of antidote stocking at hospitals in north Palestine based on published guidelines for antidote stocking.
Al-Jabi W, Samah, Sawalha F, Ansam, Sweileh M, Waleed, Zyoud H, Sa'ed   +3 more
core   +1 more source

In Vitro and Clinical Evaluations of UGT1A1‐, P‐gp‐, OATP1B1‐, and BCRP‐Mediated Drug–Drug Interactions of Belumosudil, a Potent ROCK2 Inhibitor

The Journal of Clinical Pharmacology, EarlyView.
Abstract Belumosudil is an oral selective rho‐associated coiled‐coil containing protein kinase 2 inhibitor, approved as a treatment for chronic graft‐versus‐host disease. Prior clinical studies demonstrated that coadministration with strong CYP3A4 inducers or proton pump inhibitors requires dose modification of belumosudil.
Olivier Schueller, Lauren Lohmer, Felix Beck, Jeegar Patel, Jasminder Sahi   +4 more
wiley   +1 more source

Maintenance digoxin after an episode of heart failure: placebo-controlled trial in outpatients. [PDF]

, 1977
Sylvia M. Dobbs, W I Kenyon, R. John Dobbs   +2 more
openalex   +1 more source

The cardiac work-loop technique:An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles [PDF]

, 2020
AJ Taberner, AM Aylin, AW Tank, CW Scott, D Burkhoff, D Mehra, DA Eisner, DM Bers, DR Varma, E Takimoto, FG Spinale, H Lüllman, J Layland, J Layland, J Layland, J Layland, J Layland, J Tallis, JI Schwartz, JJ Lynch, JL Holtzman, JR Blinks, JS Landzberg, K Noguchi, K Sagawa, KC Vinnakota, L Batista, L Brown, L Butler, L Guo, LJ Mellors, M Eichelbaum, M Gharanei, MA Rosic, ME Conolly, MF Peters, MS Parmacek, P Bergson, R Beigel, R Josephson, R Lewis, R Seifert, R Zhang, RA Nishimura, RC Heel, RD Olson, RK Josephson, RM Bell, RS James, T Akera, T Bombardini, T Delhaas, VJ Caiozzo, W Kerns, W Semafuko, WA Catterall, Y Kihara   +56 more
core   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

Cardiac arrhythmias induced by hypokalaemia and potassium loss during maintenance digoxin therapy. [PDF]

, 1976
Eva Steiness, Knud H. Olesen
openalex   +1 more source

Multimodal Prehabilitation for Colorectal Cancer Patients: Study Protocol of a Nationwide Multicentre Study With Uniform Prehabilitation Protocols

World Journal of Surgery, EarlyView.
The aim of prehabilitation is to optimize patient specific modifiable risk factors before major surgery, in order to enhance the individual resilience. Due to the lack of universal guidelines, prehabilitation has been conducted in various ways, making it difficult to estimate its effect.
C. R. Sabajo, J. P. Dieleman, J. W. T. Dekker, B. van den Heuvel, J. M. Klaase, G. D. Slooter   +5 more
wiley   +1 more source

Maintenance Digoxin in Elderly Patients [PDF]

, 1970
J. L. C. Dall
openalex   +1 more source