Results 11 to 20 of about 43,790 (236)
Frontiers in Cardiovascular Medicine, 2021 Background: Whether digoxin is associated with increased mortality in atrial fibrillation (AF) remains controversial. We aimed to assess the risk of mortality and clinical effects of digoxin use in patients with AF.Methods: PubMed, Embase, and the ...
Xiaoxu Wang, Yi Luo, Dan Xu, Kun Zhao
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Iranian Journal of Allergy, Asthma and Immunology, 2000 In this study we produced and purified a high titer of specific and high affin¬ity Fab fragments of anti-digoxin antibody. Immunization of rabbits with a conju¬gate of the cardiac glycoside digoxin, coupled by a periodate oxidation method to the amino ...
M. Pour-Amir +4 more
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Frontiers in Cardiovascular Medicine, 2023 The current recommendations for monitoring digoxin, a narrow therapeutic index drug, are limited to confirming medication use or investigating suspicion of toxicity and fail our oath to do no harm.
Sridhar Rao Gona +5 more
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International Journal of Medical Toxicology and Forensic Medicine, 2021 Background: Digoxin is extensively prescribed for cardiac diseases, so its chronic or acute toxicity commonly occur. Although digoxin specific antibodies (anti-digoxin Fab) are recommended to be used in patients with cardiac ...
Farzad Gheshlagh +7 more
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Interaction between Chinese medicine and digoxin: Clinical and research update
Frontiers in Pharmacology, 2023 Background: Digoxin is one of the most widely and commonly used cardiac drug, which plays an irreplaceable role in treating heart failure and arrhythmia.
Wei Zhuang +6 more
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In Vitro and Clinical Evaluation of Potential Interactions of Bemnifosbuvir with Drug Transporters. [PDF]
J Clin PharmacolAbstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug candidate for the treatment of chronic hepatitis C virus infection. Potential drug–drug interactions (DDIs) of bemnifosbuvir as a substrate or perpetrator with regard to ATP‐binding cassette (ABC) and solute carrier (SLC) transporters were evaluated in vitro and in clinical studies ...
Zhou XJ +9 more
europepmc +2 more sources
A 5 years assessment of patients with acute digoxin poisoning: A toxicoepidemiology study in Iran
Heart Views, 2021 Background: Digoxin poisoning leads to the development of cardiac and noncardiac complications. Digoxin immune fab is a safe and effective antidote, but clinical trials have not been performed in this regard, and most of the evidence is based on ...
Mitra Rahimi +3 more
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Clinical signs and symptoms of toxic serum digoxin levels in neonates
The Turkish Journal of Pediatrics, 2019 Digoxin is widely used in the treatment of congestive heart failure and some arrhythmias. Digoxin toxicity may occur easily because digoxin has a narrow therapeutic index.
Mehmet Mutlu +4 more
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‘Digoxin conundrum – Time for validation?’
Indian Heart Journal, 2021 Despite no incontrovertible data, Digoxin use has been demonised. As a consequence, a lot of patients, stable on Digoxin, have been taken off it and offered alternative drugs.
O.P. Yadava
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The effect of digoxin on renal function in patients with heart failure
BMC Nephrology, 2021 Introduction Digoxin is used in patients with chronic heart failure (CHF) who remain symptomatic despite optimal medical treatment. Impaired renal function is commonly associated with CHF.
Parin Shah +5 more
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