Results 11 to 20 of about 35,085 (202)

Effect of Digoxin Therapy on Mortality in Patients With Atrial Fibrillation: An Updated Meta-Analysis

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Whether digoxin is associated with increased mortality in atrial fibrillation (AF) remains controversial. We aimed to assess the risk of mortality and clinical effects of digoxin use in patients with AF.Methods: PubMed, Embase, and the ...
Xiaoxu Wang, Yi Luo, Dan Xu, Kun Zhao
doaj   +1 more source

Review: Failure of current digoxin monitoring for toxicity: new monitoring recommendations to maintain therapeutic levels for efficacy

open access: yesFrontiers in Cardiovascular Medicine, 2023
The current recommendations for monitoring digoxin, a narrow therapeutic index drug, are limited to confirming medication use or investigating suspicion of toxicity and fail our oath to do no harm.
Sridhar Rao Gona   +5 more
doaj   +1 more source

Clinical signs and symptoms of toxic serum digoxin levels in neonates

open access: yesThe Turkish Journal of Pediatrics, 2019
Digoxin is widely used in the treatment of congestive heart failure and some arrhythmias. Digoxin toxicity may occur easily because digoxin has a narrow therapeutic index.
Mehmet Mutlu   +4 more
doaj   +1 more source

Interaction between Chinese medicine and digoxin: Clinical and research update

open access: yesFrontiers in Pharmacology, 2023
Background: Digoxin is one of the most widely and commonly used cardiac drug, which plays an irreplaceable role in treating heart failure and arrhythmia.
Wei Zhuang   +6 more
doaj   +1 more source

A 5 years assessment of patients with acute digoxin poisoning: A toxicoepidemiology study in Iran

open access: yesHeart Views, 2021
Background: Digoxin poisoning leads to the development of cardiac and noncardiac complications. Digoxin immune fab is a safe and effective antidote, but clinical trials have not been performed in this regard, and most of the evidence is based on ...
Mitra Rahimi   +3 more
doaj   +1 more source

‘Digoxin conundrum – Time for validation?’

open access: yesIndian Heart Journal, 2021
Despite no incontrovertible data, Digoxin use has been demonised. As a consequence, a lot of patients, stable on Digoxin, have been taken off it and offered alternative drugs.
O.P. Yadava
doaj   +1 more source

Bioavailability of Digoxin and Beta-Methyl-Digoxin

open access: yesJournal of International Medical Research, 1976
In a randomized crossover study the bioavailability of a single dose of digoxin and of beta-methyl-digoxin tablets was tested in four normal volunteers. No difference was found between the two products in the rate and extent of drug absorption using 6 day cumulative urinary excretion and serial serum concentration measurements.
L, Padeletti   +3 more
openaire   +2 more sources

Digoxin and Amiodarone on the Risk of Ischemic Stroke in Atrial Fibrillation: An Observational Study

open access: yesFrontiers in Pharmacology, 2018
Purpose: The present study compared the risk of ischemic stroke in atrial fibrillation (AF) patients receiving digoxin and amiodarone.Methods: A retrospective cohort study was conducted using the longitudinal population-based database of Taiwan’s ...
Kuan-Cheng Lai   +13 more
doaj   +1 more source

The effect of digoxin on renal function in patients with heart failure

open access: yesBMC Nephrology, 2021
Introduction Digoxin is used in patients with chronic heart failure (CHF) who remain symptomatic despite optimal medical treatment. Impaired renal function is commonly associated with CHF.
Parin Shah   +5 more
doaj   +1 more source

Tissue digoxin concentrations and digoxin effect during the quinidine-digoxin interaction

open access: yesJournal of the American College of Cardiology, 1985
Quinidine elevates serum digoxin concentration in part by reducing the volume of distribution of digoxin, which implies that quinidine displaces digoxin from tissues. The purposes of this study were to: 1) measure the effect of quinidine on tissue digoxin concentrations, and 2) determine if quinidine alters the relation between myocardial digoxin ...
Warner, Natalie J.   +2 more
openaire   +2 more sources

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