Results 21 to 30 of about 62,419 (246)
Frontiers in Cardiovascular Medicine, 2021 Background: Whether digoxin is associated with increased mortality in atrial fibrillation (AF) remains controversial. We aimed to assess the risk of mortality and clinical effects of digoxin use in patients with AF.Methods: PubMed, Embase, and the ...
Xiaoxu Wang, Yi Luo, Dan Xu, Kun Zhao
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International Journal of Medical Toxicology and Forensic Medicine, 2021 Background: Digoxin is extensively prescribed for cardiac diseases, so its chronic or acute toxicity commonly occur. Although digoxin specific antibodies (anti-digoxin Fab) are recommended to be used in patients with cardiac ...
Farzad Gheshlagh +7 more
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Frontiers in Cardiovascular Medicine, 2023 The current recommendations for monitoring digoxin, a narrow therapeutic index drug, are limited to confirming medication use or investigating suspicion of toxicity and fail our oath to do no harm.
Sridhar Rao Gona +5 more
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The cardiac work-loop technique:An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles [PDF]
, 2020 The cardiac work-loop technique closely mimics the intrinsic in vivo movement and characteristics of cardiac muscle function. In this study, six known inotropes were profiled using the work-loop technique to evaluate the potential of this method to ...
AJ Taberner +56 more
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Interaction between Chinese medicine and digoxin: Clinical and research update
Frontiers in Pharmacology, 2023 Background: Digoxin is one of the most widely and commonly used cardiac drug, which plays an irreplaceable role in treating heart failure and arrhythmia.
Wei Zhuang +6 more
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Clinical signs and symptoms of toxic serum digoxin levels in neonates
The Turkish Journal of Pediatrics, 2019 Digoxin is widely used in the treatment of congestive heart failure and some arrhythmias. Digoxin toxicity may occur easily because digoxin has a narrow therapeutic index.
Mehmet Mutlu +4 more
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The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat [PDF]
, 2010 The effect of Pgp induction in rats by pregnenolone 16α-carbonitrile (PCN) (3 days, 35 mg/kg/d, p.o.) on digoxin pharmacokinetics and intestinal transport has been assessed.
Anna-Lena Ungell +12 more
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A 5 years assessment of patients with acute digoxin poisoning: A toxicoepidemiology study in Iran
Heart Views, 2021 Background: Digoxin poisoning leads to the development of cardiac and noncardiac complications. Digoxin immune fab is a safe and effective antidote, but clinical trials have not been performed in this regard, and most of the evidence is based on ...
Mitra Rahimi +3 more
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‘Digoxin conundrum – Time for validation?’
Indian Heart Journal, 2021 Despite no incontrovertible data, Digoxin use has been demonised. As a consequence, a lot of patients, stable on Digoxin, have been taken off it and offered alternative drugs.
O.P. Yadava
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Characterisation of the Na, K pump current in atrial cells from patients with and without chronic atrial fibrillation [PDF]
, 2003 <b>Objective:</b> To assess the contribution of the Na, K pump current (<i>I</i><sub>p</sub>) to the action potential duration (APD) and effective refractory period (ERP) in human atrial cells, and to investigate ...
Kane, K.A., Rankin, A.C., Workman, A.J.
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