Results 21 to 30 of about 92,853 (340)

The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat [PDF]

, 2010
The effect of Pgp induction in rats by pregnenolone 16α-carbonitrile (PCN) (3 days, 35 mg/kg/d, p.o.) on digoxin pharmacokinetics and intestinal transport has been assessed.
Anna-Lena Ungell, Bauer, Britt-Marie Fihn, Constanze Hilgendorf, Englund, Harrison, Iain S. Haslam, Johan E. Karlsson, Lam, Nicholas L. Simmons, Noe, Read, Simon Lowes   +12 more
core   +2 more sources

The effect of digoxin on renal function in patients with heart failure

BMC Nephrology, 2021
Introduction Digoxin is used in patients with chronic heart failure (CHF) who remain symptomatic despite optimal medical treatment. Impaired renal function is commonly associated with CHF.
Parin Shah, Pierpaolo Pellicori, Ian Hanning, Jufen Zhang, Andrew L. Clark, Sunil Bhandari   +5 more
doaj   +1 more source

Labeless and reversible immunosensor assay based upon an electrochemical current-transient protocol [PDF]

, 2003
A novel labeless and reversible immunoassay based upon an electrochemical current-transient protocol is reported which offers many advantages in comparison to classical immuno-biochemical analyses in terms of simplicity, speed of response, reusability
Davis, Frank, Gibson, Timothy D., Grant, Sarah, Higson, Seamus P. J., Law, Karen A., Pritchard, Jeanette A.   +5 more
core   +1 more source

Digitalis for treatment of heart failure in patients in sinus rhythm [PDF]

, 2014
<b>Background</b><p></p> Digitalis glycosides have been in clinical use for the treatment of heart failure (HF) for longer than 200 years.
Dans, Antonio L, Guyatt, Gordon H, Hood, Jr., William B, Jaeschke, Roman, McMurray, John JV   +4 more
core   +1 more source

Fetal Tachyarrhythmia - Part II: Treatment [PDF]

, 2004
The decision to initiate pharmacological intervention in case of fetal tachycardia depends on several factors and must be weighed against possible maternal and/or fetal adverse effects inherent to the use of antiarrhythmics. First, the seriousness of the
Meijboom, Erik J, Oudijk, Martijn A, Visser, Gerard HA   +2 more
core   +6 more sources

Digoxin net secretory transport in bronchial epithelial cell layers is not exclusively mediated by P-glycoprotein/MDR1 [PDF]

, 2013
Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use ...
Acharya, Alan Brown, Anne Cooper, Bleasby, Bosquillon, Bourasset, Böhme, Childs, Constanze Hilgendorf, Cynthia Bosquillon, David I. Pritchard, David Y.S. Chau, Draheim, Endter, Forbes, Forbes, Glaeser, Goda, Grainger, Gribar, Haghi, Hamilton, Hilgendorf, Huang, Kimoto, Kramer, Kullak-Ublick, Kuteykin-Teplyakov, Letschert, Letschert, Lin, Lowes, Madlova, Mamlouk, Manford, Mease, Mechetner, Mechetner, Mikkaichi, Molnár, Mukherjee, Park, Peters, Rautio, Scheffer, Sereš, Smith, Sporty, Taub, Urquhart, Vanessa Zann, Victoria Hutter, Wang, Yamaguchi, Zhou   +54 more
core   +1 more source

Pharmacokinetics, Safety, and Efficacy of Intravitreal Digoxin in Preclinical Models for Retinoblastoma [PDF]

, 2015
PURPOSE:To assess in vitro cytotoxic activity and antiangiogenic effect, ocular and systemic disposition, and toxicity of digoxin in rabbits after intravitreal injection as a potential candidate for retinoblastoma treatment.METHODS:A panel of two ...
Abramson, David, Arana, Eloisa, Buitrago, Emiliano, Chantada, Guillermo Luis, Croxatto, Juan Oscar, del Sole, Maria Jose, Djaballah, Hakim, Francis, Jasmine, Laurent, Viviana Eunice, Mena, Hebe Agustina, Negrotto, Soledad, Schaiquevich, Paula Susana, Sgroi, Mariana, Winter, Ursula Andrea   +13 more
core   +2 more sources

Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019

American Journal of Medicine Open, 2023
Background: Studies show that digoxin use is declining but is still prevalent. Recent data on digoxin prescription and characteristics of digoxin prescribers are unknown, which can help understand its contemporary use. Methods: Using Medicare Part D data
Claudia See, Kevin M. Wheelock, César Caraballo, Rohan Khera, Amarnath Annapureddy, Shiwani Mahajan, Yuan Lu, Harlan M. Krumholz, Karthik Murugiah   +8 more
doaj  

Digoxin–mortality: randomized vs. observational comparison in the DIG trial

European Heart Journal, 2019
Aims The Digitalis Investigation Group (DIG) trial, the only large randomized trial of digoxin in heart failure, reported a neutral effect on mortality and a significant reduction in heart failure hospitalizations.
L. Aguirre Dávila, K. Weber, U. Bavendiek, J. Bauersachs, J. Wittes, S. Yusuf, A. Koch   +6 more
semanticscholar   +1 more source

Declining risk of sudden death in heart failure [PDF]

, 2017
No abstract ...
Jhund, Pardeep S., McMurray, John J.V., Shen, Li   +2 more
core   +1 more source