Digoxin and Amiodarone on the Risk of Ischemic Stroke in Atrial Fibrillation: An Observational Study
Purpose: The present study compared the risk of ischemic stroke in atrial fibrillation (AF) patients receiving digoxin and amiodarone.Methods: A retrospective cohort study was conducted using the longitudinal population-based database of Taiwan’s ...
Kuan-Cheng Lai +13 more
doaj +1 more source
Mihai Gheorghiade, MD-Life and Concepts [PDF]
How do you capture an idea, shape it, and then bring it into the world? Of his many talents, this ability was a fundamental characteristic of Mihai Gheorghiade.
Butler, Javed +3 more
core +1 more source
Potential P-Glycoprotein-Mediated Drug-Drug Interactions of Antimalarial Agents in Caco-2 cells [PDF]
Antimalarials are widely used in African and Southeast Asian countries, where they are combined with other drugs for the treatment of concurrent ailments.
Horie, Toshiharu +3 more
core +1 more source
Bioavailability of Digoxin and Beta-Methyl-Digoxin
In a randomized crossover study the bioavailability of a single dose of digoxin and of beta-methyl-digoxin tablets was tested in four normal volunteers. No difference was found between the two products in the rate and extent of drug absorption using 6 day cumulative urinary excretion and serial serum concentration measurements.
L Padeletti +3 more
openaire +3 more sources
Labeless and reversible immunosensor assay based upon an electrochemical current-transient protocol [PDF]
A novel labeless and reversible immunoassay based upon an electrochemical current-transient protocol is reported which offers many advantages in comparison to classical immuno-biochemical analyses in terms of simplicity, speed of response, reusability
Davis, Frank +5 more
core +1 more source
Tissue digoxin concentrations and digoxin effect during the quinidine-digoxin interaction
Quinidine elevates serum digoxin concentration in part by reducing the volume of distribution of digoxin, which implies that quinidine displaces digoxin from tissues. The purposes of this study were to: 1) measure the effect of quinidine on tissue digoxin concentrations, and 2) determine if quinidine alters the relation between myocardial digoxin ...
Natalie J. Warner +2 more
openaire +3 more sources
Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu +3 more
core +1 more source
Digoxin Suppresses Tumor Malignancy through Inhibiting Multiple Src-Related Signaling Pathways in Non-Small Cell Lung Cancer. [PDF]
Non-small cell lung cancer is the predominant type of lung cancer, resulting in high mortality worldwide. Digoxin, a cardiac glycoside, has recently been suggested to be a novel chemotherapeutic agent.
Sheng-Yi Lin +7 more
doaj +1 more source
Recognize and Treatment of Digitalis Intoxication
Background: Digitalis is the oldest compound in cardiovascular medicine that continues to be used in contemporary clinical practice. It is one of the most frequently prescribed medications and has historically been implicated as one of the most common ...
Dewi H Suprobo +3 more
doaj +1 more source
Digoxin use after diagnosis of prostate cancer and survival: a population-based cohort study [PDF]
PURPOSE:Preclinical studies have shown that digoxin exerts anticancer effects on different cancer cell lines including prostate cancer. A recent observational study has shown that digoxin use was associated with a 25% reduction in prostate cancer risk ...
Cardwell, Chris R. +3 more
core +1 more source

