Results 91 to 100 of about 567,985 (207)

DIGOXIN TOXICITY, COMMON COLD AND HYPOTENSION [PDF]

open access: yes
Digoxin is an important cardiac drug that is widely used in clinical practice. The important concern is on the digoxin toxicity. The toxicity might sometimes come in atypical presentation.
BEHERA, GOURHARI
core  

The serum digoxin test and digoxin toxicity: a Bayesian approach to decision making.

open access: yes, 1981
The clinician may often be uncertain about the presence of digoxin toxicity. This uncertainty is particularly important when the clinician must make initial therapeutic decisions about continuing or discontinuing digoxin.
S A Eraker, L Sasse
core   +1 more source

Leveraging Healthy Volunteers for Anticancer Drug Clinical Pharmacology Studies: A Review Article Featuring Futibatinib as an Example

open access: yesClinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Early clinical development of anticancer drugs traditionally focused on exploring candidate treatments in patients. For instance, due to their cytotoxic action, administration of chemotherapies to healthy volunteers (HVs) for evaluation of their pharmacokinetic profiles was not considered feasible nor ethical from a safety and tolerability ...
Aernout D. van Haarst   +5 more
wiley   +1 more source

Design and Implementation of a Digital Escape Room Game for Teaching Pharmacy Students about Digoxin Toxicity and Its Comparison with Lecture-based Teaching Methods [PDF]

open access: yesFuture of Medical Education Journal
Background: The aim of this study was to design and implement a web-based escape room game to teach pharmacy students about digoxin poisoning and to compare it with traditional lecture-based education in terms of learning and student interaction. Method:
Milad Chahardori   +4 more
doaj   +1 more source

A SHAP‐Informed Formal Feature Attribution Framework for Drug–Drug Interaction Risk in Large‐Scale Claims Data

open access: yesClinical and Translational Science, Volume 19, Issue 9, September 2026.
ABSTRACT Pairwise drug–drug interaction databases flag co‐prescribed pairs, but they under‐weight multi‐drug combinations that drive adverse drug events in older adults. We studied that gap in Virginia All‐Payer Claims Database records (2016–2019) for adults aged 65–114 years with non‐opioid emergency department visits (n = 1182 cases; 16,105 matched ...
R. Jerome Dixon, Elvin T. Price
wiley   +1 more source

Digoxin serum levels in patients with Chagas' cardiomyopathy and heart failure Níveis séricos de digoxina em pacientes com insuficiência cardíaca secundária à cardiomiopatia da doença de Chagas

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: The purpose of this study was to determine digoxin serum concentrations in patients with Chagas' cardiomyopathy with chronic heart failure, because little is known concerning this laboratory test in patients with this condition.
Samira Jorge Ferrari   +3 more
doaj   +1 more source

Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 3, Page 554-567, September 2026.
ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma   +6 more
wiley   +1 more source

Bidirectional ventricular tachycardia with myocardial infarction: A case report with insight on mechanism and treatment

open access: yesIndian Heart Journal, 2014
Bidirectional ventricular tachycardia (BVT) is a rare variety of tachycardia with morphologically distinct presentation: The QRS axis and/or morphology is alternating in the frontal plane leads.
Abdul Wase   +4 more
doaj   +1 more source

Digoxin–Macrolide Drug Interaction

open access: yes, 1997
Macrolide antibiotics appear to be able to enhance the oral bioavailability of digoxin by altering the gastrointestinal flora that metabolize digoxin to less active dihydro metabolites, thus leading to increased serum digoxin concentrations and possible
Eric D Bizjak, Vincent F Mauro
core   +1 more source

The measurement of Digoxin serum level (DSL) in patients with heart disease and its relation with age

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2005
Background and objective: With regard to the extensive use of digoxin in patients with heart disease and its high prevalence of toxicity, this study was done to measure the digoxin serum level (DSL) in patients with or without symptoms of poisoning and ...
MT Salehi Omran   +3 more
doaj  

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