Results 121 to 130 of about 24,273 (376)
Synthesis of the d- and l-3: 4-dihydroxyphenylalanines [PDF]
C. R. Harington, Sydney Stewart Randall
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CONTEXT Catecholamine excess is rare, but symptoms may be life threatening. OBJECTIVE The objective of the study was to investigate the sensitivity of 6-[F-18]fluoro-l-dihydroxyphenylalanine positron emission tomography ((18)F-DOPA PET), compared with (
H. Fiebrich+12 more
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1.Developing food‐grade probiotic strains with smoking reduction benefits presents a safer and more holistic health strategy. 2.An animal study demonstrated that L. fermentum GKF3 gavage elevated brain dopamine and serotonin levels. 3.A randomized controlled trial showed that L.
You‐Shan Tsai+6 more
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The accumulation of l-3:4-dihydroxyphenylalanine in the tyrosinase-tyrosine reaction [PDF]
William C. Evans, Henry Stanley Raper
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Endogenous 3,4-Dihydroxyphenylalanine and Dopaquinone Modifications on Protein Tyrosine
Oxidative modifications of protein tyrosines have been implicated in multiple human diseases. Among these modifications, elevations in levels of 3,4-dihydroxyphenylalanine (DOPA), a major product of hydroxyl radical addition to tyrosine, has been ...
Xu Zhang+14 more
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Challenges in the management of Phenylketonuria in Malta [PDF]
Phenylketonuria (PKU) is a rare metabolic disorder comprising a number of different enzyme deficiencies. In Malta, dihydropteridine reductase (DHPR) deficiency appears to be more common than phenylalanine hydroxylase deficiency (classical PKU), and is ...
Attard Montalto, Simon, Attard, Stephen
core
Antiparkinsonian efficacy of guanosine in rodent models of movement disorder [PDF]
Guanosine (GUO) is a guanine-based purine nucleoside with important trophic functions and promising neuroprotective properties. Although the neuroprotective effects of GUO have been corroborated in cellular models of Parkinson's disease (PD), its ...
Ciruela Alférez, Francisco+5 more
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Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
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A comparative study of the production of l-3:4-dihydroxyphenylalanine from tyrosine by tyrosinase from various sources [PDF]
William C. Evans, Henry Stanley Raper
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Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang+12 more
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