Results 121 to 130 of about 20,405 (323)

D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]

, 2005
Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D., Barghshoon, Sami, Chen, Ching-Kang, Cheyette, Benjamin N. R., Ebert, Jana, Kovoor, Abraham, Lester, Henry A., Schwarz, Johannes, Schwarz, Sigrid, Seyffarth, Petra, Simon, Melvin I.   +10 more
core  

Congenital Hyperinsulinism: Pancreatic [¹⁸F]Fluoro-l-Dihydroxyphenylalanine (DOPA) Positron Emission Tomography and Immunohistochemistry Study of DOPA Decarboxylase and Insulin Secretion [PDF]

, 2006
Pascale de Lonlay, Aurore Simon-Carré, Maria-João Ribeiro, Nathalie Boddaert, Irina Giurgea, Kathleen Laborde, Christine Bellanné‐Chantelot, Virginie Verkarre, Michel Polak, Jacques Rahier, André Syrota, David Seidenwurm, Claire Nihoul‐Feketé, Jean‐Jacques Robert, Françis Brunelle, Francis Jaubert   +15 more
openalex   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

The Interaction of Histamine H₃ and Dopamine D₁ Receptors on Hyperkinetic Alterations in Animal Models of Parkinson’s Disease

Pharmaceuticals
Parkinson’s disease is associated with the loss of more than 40% of dopaminergic neurons in the substantia nigra pars compacta. One of the therapeutic options for restoring striatal dopamine levels is the administration of L-3,4-dihydroxyphenylalanine (L-
Alberto Avila-Luna, Antonio Verduzco-Mendoza, Adriana Olmos-Hernández, José Luis Cortes-Altamirano, Alfonso Alfaro-Rodríguez, José-Antonio Arias-Montaño, Antonio Bueno-Nava   +6 more
doaj   +1 more source

Photoelectrochemical properties of melanin [PDF]

, 2007
Melanin is to the animal kingdom like chlorophyll to the vegetal kingdom(1). Melanin collects energy from lower-energy radiation sources, kicks electrons into excited states, initiating a process that would end up producing chemical energy, similar to ...
Arturo Solis, Luis E. Rendon, Maria E. Lara   +2 more
core   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

The Phenoloxidases of the Ascomycete Podospora anserina Structural Differences between Laccases of High and Low Molecular Weight [PDF]

, 1978
Esser, Karl, Klischies, Martina, Minuth, Walter   +2 more
core   +1 more source

Mechanical Reinforcement of Polymer Nanocomposites with Different Network Structure of Polymer Grafted Nanoparticles

Macromolecular Materials and Engineering, EarlyView.
Due to the different conformation structures of the grafting chains on the surface of silica, the nanoparticles contact each other by brush chains and bridge into a polymer‐mediated nanoparticle network in HDPE14K/HDPE1K‐g‐SiO2 PNCs, resulting in a more significant modulus reinforcement than that of PP370K/PP90K‐g‐SiO2 PNCs with a soft interfacial ...
Ye Yao, Shaofan Li, Weilong Ju, Yunlan Su, Dujin Wang   +4 more
wiley   +1 more source

A novel approach to tyrosinase-based biosensors: Electrode reactions and biological measurement

Biosensors and Bioelectronics: X
This study introduces a novel tyrosinase-based biosensor designed to simultaneously detect tyrosinase, tyrosine, L-DOPA, and L-DOPA quinone. The biosensor, designated as GCE/GNP/Cys/Chit/Tyrase, was developed by immobilizing tyrosinase on a modified ...
Masumeh Goodarzi, Hosna Tavakoli, Maryam Arab Khalaj, Hassan Tavakoli   +3 more
doaj   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source