Results 141 to 150 of about 11,930 (298)
A Novel Mouse Model of Sympathoadrenal Catecholamine Deficiency by Ablation of the Tyrosine Hydroxylase Gene With Slc6a4-Cre. [PDF]
Ogawa R +4 more
europepmc +1 more source
D- and L-dihydroxyphenylalanine (D- and L-DOPA) and enantiomers of the tetrahydroisoquinoline alkaloids salsolinol (SAL), 1-carboxysalsolinol (1-CSAL), and cis-3-carboxysalsolinol (3-CSAL) were chromatographed using sulfated beta -cyclodextrin (S-beta ...
McMurtrey, K. +2 more
core
Severe Lower Limb and Abdominal Edema Associated with Subcutaneous Apomorphine Infusion
Movement Disorders Clinical Practice, EarlyView.
Guillaume Costentin, David Maltête
wiley +1 more source
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss +10 more
wiley +1 more source
A case report of blood pressure fluctuation, inverted Takotsubo cardiomyopathy, and pulmonary embolism: searching for a link. [PDF]
Mazza A +4 more
europepmc +1 more source
Abstract Background The identification of Parkinson's disease (PD) subtypes is crucial for predicting the disease course and designing personalized therapeutic strategies. Objectives The aim of the study was to characterize the heterogeneity of the spatiotemporal evolutionary patterns of striatal dopamine depletion and cerebral hypoperfusion in PD ...
Yeeun Sun +9 more
wiley +1 more source
Newborn metabolomic perturbations associated with prenatal tobacco smoke exposure and early birth. [PDF]
Nesbeth PC +15 more
europepmc +1 more source
The complete amino acid sequence of pig kidney 3,4-dihydroxyphenylalanine (Dopa) decarboxylase is reported. The sequence was determined from analysis of peptides isolated after tryptic and cyanogen bromide cleavages of the enzyme. Each subunit is made up
VOLTATTORNI, Carla +4 more
core
Abstract Background Intracerebral gene therapy is effective for amino acid decarboxylase (AADC) deficiency, but relationships between anatomical putaminal coverage, metabolic dynamics, and clinical recovery remain poorly understood. Objectives Assess safety, long‐term efficacy, and clinical–radiological correlations in a genetically diverse European ...
Clément Dunoyer +27 more
wiley +1 more source
Metal anchoring strategy: electrochemical sensor with excellent performance in gastrointestinal secretions. [PDF]
Ji J +6 more
europepmc +1 more source

