Results 151 to 160 of about 25,647 (343)
Phenotypic Clues in Infantile‐Onset Parkinsonism‐Dystonia‐2: A Treatable Neurotransmitter Disorder
Movement Disorders Clinical Practice, EarlyView.
Sangeetha Yoganathan +10 more
wiley +1 more source
Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease
Neuroprotection, EarlyView.Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García +7 more
wiley +1 more source
Molecular and cellular determinants of L-Dopa-induced dyskinesia in Parkinson’s Disease
npj Parkinson's DiseaseTreatment with L-3,4-dihydroxyphenylalanine (L-Dopa) compensates for decreased striatal dopamine (DA) levels and reduces Parkinson’s disease (PD) symptoms.
Federica Servillo +22 more
doaj +1 more source
L‐tyrosine and L‐dihydroxyphenylalanine as hormone‐like regulators of melanocyte functions
Pigment Cell & Melanoma Research, 2012 A. Slominski, M. Żmijewski, J. Pawelek
semanticscholar +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Portal Hypertension &Cirrhosis, EarlyView.Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source
Current Insight into Human Ornithine Aminotransferase: A Review
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Human ornithine aminotransferase (hOAT) is a mitochondrial matrix pyridoxal‐5′‐phosphate enzyme (PLP) that catalyzes the reversible transfer of the δ‐amino group of L‐ornithine (L‐Orn) to α‐ketoglutarate (α‐KG) yielding glutamate‐5‐semialdehyde (GSA) and glutamate. GSA is prone to cyclize to Δ1‐pyrroline‐5‐carboxylate.
Fulvio Floriani +2 more
wiley +1 more source
Vitae, 2009 Skin pigmentation is the consequence of melanin production and dispersion, this pigment is formed by a successive oxidation of L-Tyrosine into L-Dihydroxyphenylalanine (L-DOPA) and dopaquinone by Tyrosinase enzyme. Skin pigmentation irregularities become
Katalina MUÑOZ D. +4 more
doaj
Advances in the Different Synthetic Routes of Fluorinated Hydrazines
The Chemical Record, EarlyView.This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye +5 more
wiley +1 more source
L-Dihydroxyphenylalanine induces melanin production by members of the genus Trichosporon.
FEMS Yeast Research, 2014 M. Figueiredo-Carvalho +4 more
semanticscholar +1 more source