Results 181 to 190 of about 24,273 (376)
Dihydroxyphenylalanine and Hydroxytyramine in Mammalian Suprarenals. [PDF]
McC. Goodall+3 more
openaire +2 more sources
ABSTRACT Background Parkinson's disease (PD) varies widely across individuals in clinical manifestations and course of progression. Identification of distinct biological subtypes could explain this heterogeneity, identify its pathophysiology, and predict disease progression. Objectives Our aim was to compare longitudinal clinical trajectories and brain
Seyed‐Mohammad Fereshtehnejad+7 more
wiley +1 more source
L‐tyrosine and L‐dihydroxyphenylalanine as hormone‐like regulators of melanocyte functions
A. Slominski, M. Żmijewski, J. Pawelek
semanticscholar +1 more source
Four Hour Temporal Relation of 5-HTP and L-DOPA Induces Inhibitory Responses in Recrudescing Gonad of Indian Palm Squirrel (Funambulus pennantii) [PDF]
C. M. Chaturvedi, Ranjana Jaiwal
core +1 more source
The Changing Face of Dystonia—Enhancing Diagnosis by Moving Beyond Traditional Clinical Phenotyping
Movement Disorders Clinical Practice, EarlyView.
Niroshan Jeyakumar, Kishore R. Kumar
wiley +1 more source
Abstract Background Breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in basal ganglia cells through hydrolysis of diesteric bonds, primarily by PDE10A and PDE1B, is essential for normal human movement. While biallelic loss‐of‐function variants in PDE10A are known to cause hyperkinetic movement disorders, the ...
Tomer Poleg+21 more
wiley +1 more source
Early Levodopa Therapy in Tyrosine Hydroxylase Deficiency
Movement Disorders Clinical Practice, EarlyView.
Claudio M. de Gusmao+4 more
wiley +1 more source
Abstract Traditionally, clinical trials of putative disease‐modifying therapies in Parkinson's disease have enrolled untreated patients at the earliest clinical stages of their disease. Due to a number of challenges inherent with this approach, there has been a recent move to a different study design, enrolling patients who are already taking “stable ...
M. Maral Mouradian+2 more
wiley +1 more source
A role for enhanced peptidergic transmission, either opioidergic or not, has been proposed for the generation of l-3,4-dihydroxyphenylalanine (l-DOPA)-induced dyskinesia (LID) on the basis of in situ hybridization studies showing that striatal ...
Mathieu Bourdenx+7 more
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