Results 201 to 210 of about 11,997 (297)

No Significant Secondary Structural Change of α‐Synuclein Monomer by Site‐Specific DOPA or Phosphorylation Introduction in Its C‐Terminal Region

Journal of Peptide Science, Volume 32, Issue 9, September 2026.
Site‐specifically modified α‐synuclein containing DOPA or phosphorylation was prepared by ligation of a bacterially expressed N‐terminal polypeptide and a synthetic C‐terminal modified peptide. ABSTRACT α‐Synuclein (αSyn) is a major component of pathogenic Lewy bodies and Lewy neurites and is closely associated with Parkinson's disease.
Tatsuhito Matsuo, Isao Suetake, Mariko Kimura, Satoshi Hashimoto, Koichi Matsuo, Sakiko Matsumoto, Shinji Hirotsune, Hironobu Hojo   +7 more
wiley   +1 more source

Multiple transitions to high l-DOPA 4,5-dioxygenase activity reveal molecular pathways to convergent betalain pigmentation in Caryophyllales. [PDF]

New Phytol
Walker-Hale N, Guerrero-Rubio MA, Brockington SF.   +2 more
europepmc   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Antioxidant, Anti-Melanogenic, and Anti-Aging Activities of the Aqueous-Ethanolic Dry Extract of <i>Rosa lucieae</i> with Phytochemical Profiling. [PDF]

Antioxidants (Basel)
Park YG, Kim JY, Ko SC, Kim KW, Yang D, Jo DM, Lee HG, Lee JM, Yim MJ, Kim CH, Lee DS, Kim HS, Oh GW.   +12 more
europepmc   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

Reduced striatal dopamine transmission as a transdiagnostic substrate of psychomotor retardation. [PDF]

Brain
Leong IL, Ng TH, Sen K, Burchill E, Costello H, Badenoch JB, Coebergh J, McCutcheon RA, Nair A, Browning M, Huys QJM, Lewis G, Lees A, David AS, Rogers JP.   +14 more
europepmc   +1 more source

Decoding chemical profiles in insect‐induced gall development: Insights from Phacopteron lentiginosum–Garuga pinnata interactions

Entomological Science, Volume 29, Issue 3, September 2026.
Analysis of volatile and non‐volatile metabolites across three developmental stages (3rd, 4th and 5th instar nymphal stages) of leaf galls induced by Phacopteron lentiginosum on Garuga pinnata revealed that the 3rd stage exhibited the highest chemical diversity and concentration followed by 4th and 5th stages.
V. K. Bobika, M. Nasser, K. S. Shameer
wiley   +1 more source

Structural insights into the substrate transport mechanism of the amino acid transporter complex. [PDF]

J Biol Chem
Yang H, Shi T, Dong J, Zhang T, Li Y, Guo Y, Yuan Y, Yang L, Dong JT, Yan R.   +9 more
europepmc   +1 more source

Staurosporine Drives Non‐Canonical Melanocyte Maturation by Coupling β‐Catenin Signaling to Actin‐Dependent Dendrite Remodeling

Pigment Cell &Melanoma Research, Volume 39, Issue 5, September 2026.
Staurosporine drives non‐canonical melanocyte maturation through β‐catenin‐dependent actin remodeling. Functional maturation enhances dendrite architecture and melanogenic differentiation without inducing melanocyte proliferation, providing a biological framework for restoring functional melanocytes in acquired hypopigmentary disorders.
Kangning Xu, Lingli Yang, Sylvia Lai, Fei Yang, Yasutaka Kuroda, Daisuke Tsuruta, Ichiro Katayama   +6 more
wiley   +1 more source

Phytochemical Profiling, Antioxidant Capacity, and α-Amylase/α-Glucosidase Inhibitory Effects of 29 Faba Bean (<i>Vicia faba</i> L.) Varieties from China. [PDF]

Biology (Basel)
Li Y, Wang Z, Mei C, Sun W, Yuan X, Wang J, Huang W, Huang W.   +7 more
europepmc   +1 more source