Results 191 to 200 of about 24,273 (376)

Studies on the Metabolism and Excretion of L-3, 4-Dihydroxyphenylalanine (L-DOPA) in Human Beings by Gas Chromatography

open access: bronze, 1972
Kazuhiro Imai   +7 more
openalex   +2 more sources

Evaluation of Induced Pluripotent Stem Cell‐Derived Dopaminergic Neurons from Siblings with Gaucher Disease Discordant for Parkinsonism

open access: yesMovement Disorders, EarlyView.
Abstract Background In Gaucher disease (GD), glucocerebrosidase (GCase) deficiency results from biallelic pathogenic GBA1 variants. While GBA1 variants are a major risk factor for Parkinson's disease (PD), most patients with GD never develop parkinsonism.
Ellen Hertz   +12 more
wiley   +1 more source

Blepharospasm in GNAO1 Syndrome May Benefit From Botulinum Toxins

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Eleonora Minacapilli   +4 more
wiley   +1 more source

Pregnenolone Reduces L‐Dopa‐Induced Dyskinesias in Female Parkinsonian Monkeys

open access: yesMovement Disorders, EarlyView.
Pregnenolone is the first neurosteroid synthesized from cholesterol in the brain. Ovariectomized female monkeys were tested as a model of women in menopause. They were lesioned with MPTP modeling Parkinson's disease and treated with levodopa (L‐dopa) to induce dyskinesias.
Mélanie Bourque   +5 more
wiley   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva   +5 more
wiley   +1 more source

Intelligent peptide‐based nanomaterials for targeted antibacterial therapy: Design, properties and applications

open access: yesResponsive Materials, EarlyView.
This review comprehensively discusses intelligent peptide‐based nanomaterials from the design, mechanisms, properties, and applications, taking stimuli responsiveness as a starting point. Abstract Bacterial infections pose a major threat to human health as well as livestock production. Traditional antibiotics face significant limitations in the complex
Chenlong Zhou   +8 more
wiley   +1 more source

Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications

open access: yesSmall Structures, EarlyView.
This review summarizes the fabrication methods, properties, and applications of conductive hydrogels in neural interfaces. Finally, the prevailing challenges and outlines of future directions in the field of conductive hydrogels for neural interfaces are provided, emphasizing the need for interdisciplinary research to address issues such as long‐term ...
Xin‐Yu Xue   +10 more
wiley   +1 more source

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