Results 291 to 300 of about 24,273 (376)

Hyperglycemia Aggravates 6‐Hydroxydopamine‐Induced Neuronal Ferroptosis via SLC7A11‐Dependent Pathway in Diabetic PD Rat Model

CNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Chronic hyperglycemia disrupts the cystine/SLC7A11/glutathione axis, impairing cystine uptake and depleting glutathione in dopaminergic neurons, increasing ferroptosis susceptibility. SLC7A11 restoration rescues neuronal viability, restores redox balance, and attenuates neurodegeneration in diabetic PD models. SLC7A11 emerges as a therapeutic target to
Ya Zhao, Dan Wang, Yanwei Wang, Dan Mu, Lang Qu, Rong Li   +5 more
wiley   +1 more source

Suppression of sleep syncope and vagally-mediated asystole by norepinephrine transporter inhibitor. [PDF]

HeartRhythm Case Rep
Rabajoli A, Raj SR, Sheldon R.
europepmc   +1 more source

Sex Differences in Motor Unit Behavior in Patients With Parkinson's Disease

European Journal of Neuroscience, Volume 62, Issue 1, July 2025.
This study utilized high‐density surface electromyography and motor unit decomposition to investigate sex differences in motor unit firing behavior in patients with Parkinson's disease. Females exhibited greater asymmetry in firing properties between more‐ and less‐affected sides, including lower estimates of persistent inward currents (ΔF), higher ...
Yuichi Nishikawa, Kohei Watanabe, Aleš Holobar, Tetsuya Takahashi, Noriaki Maeda, Hirofumi Maruyama, Allison Hyngstrom   +6 more
wiley   +1 more source

Inhibitory Effect of 505 nm Green Light Emitting Diode on Melanin Synthesis in Cellular Experiments and a Human Intervention Study. [PDF]

Acta Derm Venereol
Mima Y, Yamada T, Omatsu J, Yamashita T, Suzuki S, Takechi T, Ichikawa M, Yamazaki K, Sato S, Yoshizaki A.   +9 more
europepmc   +1 more source

Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy [PDF]

, 1984
Berlit, Peter, Bonjour, Jean-Pierre, Kochen, W., Krause, Klaus-Henning   +3 more
core  

Pathogenesis of Melasma Explained

International Journal of Dermatology, Volume 64, Issue 7, Page 1201-1212, July 2025.
Pathophysiology of melasma. ABSTRACT This review provides an in‐depth analysis of the pathophysiology of melasma and highlights recent studies that elucidate its underlying mechanisms. Given the prevalence of melasma, a thorough understanding of its pathogenesis is critical for the development of effective treatment strategies.
Lara Ali, Firas Al Niaimi
wiley   +1 more source

The Orthovanadate-Catalyzed Formation of a Thermally Inert and Low-Redox-Potential Melanin. [PDF]

Int J Mol Sci
VanArsdale E, Atoyebi O, Nag O, Laskoski M, Glaser E, Oh E, Vora GJ, Wang Z.   +7 more
europepmc   +1 more source

The gut‐microbiota‐brain axis: Focus on gut steroids

Journal of Neuroendocrinology, Volume 37, Issue 7, July 2025.
Abstract There are over 1000 varieties of steroids that have been reported in nature, including the endogenous sex steroid hormones (i.e., progesterone, testosterone, and 17β‐estradiol) and corticosteroids which are mainly synthesized by gonads and adrenals, respectively.
Silvia Diviccaro, Silvia Giatti, Lucia Cioffi, Gabriela Chrostek, Roberto Cosimo Melcangi   +4 more
wiley   +1 more source

Construction of Large-Scale Bioengineered Hair Germs and In Vivo Transplantation. [PDF]

Adv Sci (Weinh)
Chen Y, Hou Y, Chen J, Bai J, Du L, Qiu C, Qi H, Liu X, Huang J.   +8 more
europepmc   +1 more source