Results 121 to 130 of about 3,309 (181)

2,5-Diketopiperazines as Neuroprotective Agents

Mini-Reviews in Medicinal Chemistry, 2012
2,5-diketopiperazines are the simplest cyclic peptides found in nature, commonly biosynthesized from amino acids by different organisms, and represent a promising class of biologically active natural products. Their peculiar heterocyclic structure confers high stability against the proteolysis and constitutes a structural requirement for the active ...
CORNACCHIA, CATIA, CACCIATORE, Ivana, BALDASSARRE, LEONARDO, MOLLICA, ADRIANO, FELICIANI, FEDERICA, PINNEN, Francesco Enrico   +5 more
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Diketopiperazines in wines

Journal of Wine Research, 2018
ABSTRACTThis study describes the identification of cyclic dipeptides known as diketopiperazines in red, white and sparkling wines from Greek market. Diketopiperazines have been isolated from bottled wines after liquid–liquid extraction and identified using gas chromatography coupled with mass spectrometry.
Eygenia Stamatelopoulou, Sofia Agriopoulou, Euthalia Dourtoglou, Arhontoula Chatzilazarou, Fotini Drosou, Marina Marinea, Vassilis Dourtoglou   +6 more
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Improvements in Aldol Reactions with Diketopiperazines.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Juan Francisco González, Elena de la Cuesta, Carmen Avendaño   +2 more
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Diketopiperazines from Marine Organisms

Chemistry & Biodiversity, 2010
AbstractDiketopiperazines (DKPs), which are cyclic dipeptides, have been detected in a variety of natural resources. Recently, the interest in these compounds increased significantly because of their remarkable bioactivity. This review deals with the chemical structures, biosynthetic pathways, and biological activities of DKPs from marine ...
Riming, Huang, Xuefeng, Zhou, Tunhai, Xu, Xianwen, Yang, Yonghong, Liu   +4 more
openaire   +2 more sources

Microbial hydrolysis of diketopiperazines: Different types of diketopiperazine-assimilating bacteria

Journal of Fermentation and Bioengineering, 1997
Abstract Arthrobacter sp. 1-3-1 and a coryneform rod bacterium, strain T-1-3-Y, which assimilate cyclo(Gly-Gly) and cyclo(Gly- l -Tyr) at high rates, respectively, were isolated from soil. Both bacteria exhibit diketopiperazine-hydrolyzing activity intracellularly in contrast to the extracellular cyclo(Gly-Gly) hydrolase reported previously ...
Hiroshi Kanzaki, Shuji Oda, Akio Kobayashi, Kazuyoshi Kawazu   +3 more
openaire   +1 more source

Diketopiperazines in Peptide and Combinatorial Chemistry

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
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SYNTHESIS OF DIKETOPIPERAZINES

Canadian Journal of Chemistry, 1963
not available
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Diketopiperazines: Biological Activity and Synthesis

ChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Maristela B. Martins, Ivone Carvalho
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Thiolation of symmetrical and unsymmetrical diketopiperazines

Org. Biomol. Chem., 2012
The introduction of sulfur units into a variety of symmetrical and unsymmetrical diketopiperazines (DKPs) is described. We investigated different thiolation methods utilizing several bases and electrophilic sulfur reagents, leading to monomethylthio-, bis(methylthio)-, and epithio-DKPs.
Ruff, B. M., Zhong, S., Nieger, M., Bräse, S.   +3 more
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Discovery of a Class of Diketopiperazines as Antiprion Compounds

ChemMedChem, 2010
AbstractPrion diseases are fatal neurodegenerative and infectious disorders for which effective pharmacological tools are not yet available. This unmet challenge and the recently proposed interplay between prion diseases and Alzheimer's have led to a more urgent demand for new antiprion agents.
BOLOGNESI ML, AI TRAN HN, STADERINI M, MONACO A, LÓPEZ COBEÑAS A, BONGARZONE S, BIARNÉS X, LÓPEZ ALVARADO P, CABEZAS N, CARAMELLI M, CARLONI P, MENÉNDEZ JC, Legname, Giuseppe   +12 more
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