Results 1 to 10 of about 261 (135)
Structures and Biological Activities of Diketopiperazines from Marine Organisms: A Review
Marine Drugs, 2021 Diketopiperazines are potential structures with extensive biological functions, which have attracted much attention of natural product researchers for a long time.
Shao-Hua Wu, Wu Shaohua
exaly +3 more sources
Efficient Microwave Assisted Syntheses of 2,5-Diketopiperazines in Aqueous Media
Molecules, 2009 Aqueous in situ one-pot N-Boc-deprotection-cyclization of Nα-Boc-dipeptidyl-tert-butyl and methyl esters under microwave irradiation afforded 2,5-diketopiperazines (DKPs) in excellent yields.
Jaime Escalante +2 more
exaly +3 more sources
Characterisation of Cooked Cheese Flavour: Non-Volatile Components
Foods, 2023 This work examined the role of selected non-volatile compounds in cooked cheese flavour, both as tastants and as precursors of aroma generation in the Maillard reaction.
Rosa C. Sullivan +5 more
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Heliyon, 2022 2,5-diketopiperazines are cyclic dipeptides found, among others, in chocolate. Although those compounds are contributing greatly to its pleasant bitterness, they can also be seen as interesting markers of cocoa beans processing. To evaluate the influence
Amandine André +3 more
doaj +1 more source
Molecules, 2021 Ten polyketide derivatives (1–10), including a new natural product named (E)-2,4-dihydroxy-3-methyl-6-(2-oxopent-3-en-1-yl) benzaldehyde (1), and five known diketopiperazines (11–15), were isolated from the mangrove-sediment-derived fungus Aspergillus sp.
Jian Cai +8 more
doaj +1 more source
Cyclodipeptides: From Their Green Synthesis to Anti-Age Activity
Biomedicines, 2022 Cyclodipeptides (CDPs) or diketopiperazines (DKPs) are often found in nature and in foodstuff and beverages and have attracted great interest for their bioactivities, biocompatibility, and biodegradability.
Veronica Mosetti +10 more
doaj +1 more source
A facile synthesis of cysteine-based diketopiperazine from thiol-protected precursor [PDF]
Royal Society Open Science, 2018 l-Cysteine is one of the most promising biomass-based building blocks with great potential applications. Herein, we report a versatile synthetic route to produce cysteine-based 2,5-diketopiperazine (DKP) with good yield from the thiol-ene click reaction ...
Di Zhang, Wayne Wang
doaj +1 more source
Chemical and Biological Studies of Endophytes Isolated from Marchantia polymorpha
Molecules, 2023 Natural bioresources, predominantly plants, have always been regarded as the richest source of drugs for diseases threatening humanity. Additionally, microorganism-originating metabolites have been extensively explored as weapons against bacterial ...
Mateusz Stelmasiewicz +2 more
doaj +1 more source
Molecules, 2021 2,5-diketopiperazines (DKPs) are cyclic dipeptides ubiquitously found in nature. In particular, cyclo(Phe-Pro), cyclo(Leu-Pro), and cyclo(Val-Pro) are frequently detected in many microbial cultures.
Alison Domzalski +6 more
doaj +1 more source
Nature Communications, 2020 Bacterial heterodimeric tryptophan-containing diketopiperazines (HTDKPs) are bioactive natural products that are difficult to access chemically. Here, the authors identify a family of three related HTDKP-forming cytochrome P450s and engineer key amino ...
Chenghai Sun +9 more
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