Results 31 to 40 of about 3,824 (213)

Dichotocejpins A–C: New Diketopiperazines from a Deep-Sea-Derived Fungus Dichotomomyces cejpii FS110

open access: yesMarine Drugs, 2016
Three new diketopiperazines, dichotocejpins A–C (1–3), together with eight known analogues (4–11), were isolated from the culture of the deep-sea sediment derived fungus Dichotomomyces cejpii FS110.
Zhen Fan   +6 more
doaj   +1 more source

Bacterial Quorum-Sensing Molecules as Promising Natural Inhibitors of Candida albicans Virulence Dimorphism: An In Silico and In Vitro Study

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Farnesol, a self-secreted quorum-sensing molecule (QSM) of Candida albicans, has been known to limit yeast-to-hyphal transition by blocking the RAS1–cAMP–PKA pathway.
Ravi Jothi   +3 more
doaj   +1 more source

A Practical Sulfenylation of 2,5‐Diketopiperazines [PDF]

open access: yesAngewandte Chemie, 2011
Sulfurs in action A practical and simple method for the introduction of sulfur atoms into 2,5-diketopiperazines (I) under mild conditions has been developed leading to more or less complex epidithiodiketopiperazines (II) and bis-methylthiodiketopiperazines (III).
K C, Nicolaou   +3 more
openaire   +2 more sources

Isolation and Structure Identification of Novel Brominated Diketopiperazines from Nocardia ignorata—A Lichen-Associated Actinobacterium

open access: yesMolecules, 2017
Actinobacteria are well known for their potential in biotechnology and their production of metabolites of interest. Lichens are a promising source of new bacterial strains, especially Actinobacteria, which afford a broad chemical diversity.
Alba Noël   +5 more
doaj   +1 more source

Research progress on activity and biosynthesis of diketopiperazines

open access: yes, 2023
Diketopiperazines (DKPs) are mainly produced by microorganisms. In recent years, active natural products with DKPs structure have been isolated from marine bacteria, actinomycetes and fungi.
Jintong Zhao   +11 more
core   +1 more source

Cyclic Dipeptides Mediating Quorum Sensing and Their Biological Effects in Hypsizygus Marmoreus

open access: yesBiomolecules, 2020
A novel quorum sensing (QS) system was discovered in Serratia odorifera, the symbiotic bacterium of Hypsizygus marmoreus. This system uses cyclo(Pro-Phe), cyclo(Pro-Tyr), cyclo(Pro-Val), cyclo(Pro-Leu), cyclo(Tyr-Leu), and cyclo(Tyr-Ile) as autoinducers.
Shu-Jing Sun   +6 more
doaj   +1 more source

Nojirimycin Based 2,5-Diketopiperazines

open access: yes, 2019
2,5-Diketopiperazines were prepared and characterized where one of the amino acids is (2S,3R,4R,5S)-3,4,5-trihydroxypipecolic acid. The protected pipecolic acid was synthesized from a selectively protected deoxynojirimycin derivative. The ring closure to
Károly Ágoston (6242306)
core   +1 more source

New Cyclotetrapeptides and a New Diketopiperzine Derivative from the Marine Sponge-Associated Fungus Neosartorya glabra KUFA 0702

open access: yesMarine Drugs, 2016
Two new cyclotetrapeptides, sartoryglabramides A (5) and B (6), and a new analog of fellutanine A (8) were isolated, together with six known compounds including ergosta-4, 6, 8 (14), 22-tetraen-3-one, ergosterol 5, 8-endoperoxide, helvolic acid ...
War War May Zin   +10 more
doaj   +1 more source

Marine Indole Alkaloids

open access: yesMarine Drugs, 2015
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development.
Natalie Netz, Till Opatz
doaj   +1 more source

Three cheers for nitrogen: aza-DKPs, the aza analogues of 2,5-diketopiperazines [PDF]

open access: yes, 2020
Nitrogen-containing heterocycles represent a major source of pharmacological probes and drug candidates. To extend their molecular diversity and their potential biological activities, it is of importance to design and synthesize new N-heterocyclic ...
Bonnet, Dominique   +4 more
core   +1 more source

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