Results 41 to 50 of about 35,924 (294)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Understanding heterogeneous mechanisms of heart failure with preserved ejection fraction through cardiorenal mathematical modeling.

PLoS Computational Biology, 2023
In contrast to heart failure (HF) with reduced ejection fraction (HFrEF), effective interventions for HF with preserved ejection fraction (HFpEF) have proven elusive, in part because it is a heterogeneous syndrome with incompletely understood ...
Sanchita Basu, Hongtao Yu, Jonathan R Murrow, K Melissa Hallow   +3 more
doaj   +1 more source

Clinical outcome of endoscopic balloon dilatations employed in benign paediatric oesophageal pathologies

Journal of Minimal Access Surgery, 2022
Background: Oesophageal dilatations can be done either by bougies or balloons for differing aetiologies in children. We investigated the efficacy and safety of endoscopic balloon dilatations (EBDs) employed by a single surgeon. Patients and Methods: Relevant data over 12 years were ...
Cigdem Ulukaya Durakbasa, Furkan Ersoy, Ahmet Pirim, Meltem Caglar Oskayli   +3 more
openaire   +3 more sources

Achalasia: A review of Western and Iranian experiences [PDF]

, 2009
Achalasia is a primary motor disorder of the esophagus, in which esophageal emptying is impaired. Diagnosis of achalasia is based on clinical findings. The diagnosis is confirmed by radiographic, endoscopic, and manometric evaluations. Several treatments
Mikaeli, J., Islami, F., Malekzadeh, R.
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical characteristics, CT signs, and pathological findings of Pyrrolizidine alkaloids-induced sinusoidal obstructive syndrome: a retrospective study

BMC Gastroenterology, 2020
Background One major etiology of hepatic sinusoidal obstruction syndrome (HSOS) in China is the intake of pyrrolizidine alkaloids (PAs). Since PAs-induced HSOS is a rare disease that has not been clearly characterized until now, the aim of this study was
Fang Liu, Xinxin Rong, Hui Guo, Dong Xu, Chang Liu, Lingling Meng, Xiaoqian Yang, Tingting Guo, Xuefeng Kan, Yuhu Song   +9 more
doaj   +1 more source

Initial diagnosis and successful treatment of pulmonary tumor embolism manifesting as the first clinical sign of prostatic adenocarcinoma

Respiratory Medicine Case Reports, 2020
Although pulmonary tumor embolism (PTE) is a well-recognized end-stage form of pulmonary metastases at postmortem examination, the entity is rarely the first clinical sign of prostate cancer.
Tananchai Petnak, Thitiporn Suwatanapongched, Wipawi Klaisuban, Chayanin Nitiwarangkul, Prapaporn Pornsuriyasak   +4 more
doaj   +1 more source

Percutaneous transhepatic cholangiography and biliary drainage after liver transplantation: A five-year experience [PDF]

, 1987
Evaluation of the biliary tract by percutaneous transhepatic cholangiography (PTC) is often required in liver transplant patients with an abnormal postoperative course.
AB Zajko, AG Tzakis, Albert B. Zajko, David H. Thiel, DH Thiel Van, DJ Gallacher, G Martineau, J Northover, JC Gartner Jr, JJ Malatack, JMA Northover, JT Ferrucci Jr, Klaus M. Bron, Rajan Behal, RY Calne, RY Calne, S Iwatsuki, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, TE Starzl, Thomas E. Starzl, W Molnar, William L. Campbell   +27 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Assessment of Hepatic Lesions After non-Thermal Tumor Ablation by Irreversible Electroporation in a Pig Model

Technology in Cancer Research & Treatment, 2023
Irreversible electroporation (IRE) is a non-thermal and minimal invasive modality to ablate pathologic lesions such as hepatic tumors. Histological analysis of the initial lesions after IRE can help predict ablation efficacy.
Sung-Min Jeon PhD, Enkhzaya Davaa PhD, Yixin Jiang PhD, Ratchapol Jenjob PhD, Ngoc-Thuan Truong Ms, Kyung-Ju Shin PhD, Seok Jeong MD, PhD, Su-Geun Yang PhD   +7 more
doaj   +1 more source