Results 101 to 110 of about 19,064 (180)

Intravenous diltiazem for termination of reentrant supraventricular tachycardia: a placebo-controlled, randomized, double-blind, multicenter study

open access: yes, 1989
To assess the efficacy and safety of intravenous diltiazem, 54 patients with inducible sustained supraventricular tachycardia received diltiazem, 0.25 mg/kg or 0.25 mg/kg, followed by 0.35 mg/kg body weight, or placebo in a double-blind, randomized study.
Dias, Virgil C   +5 more
core   +1 more source

Spectrophotometric determination of diltiazem in dosage forms

open access: yes, 1992
A simple and reproducible method for determination of diltiazem in bulk and in dosage forms is presented. The method is based on formation of hydroxamic acid, which reacts with iron (III), forming a complex with a maximum absorption at 525nm.
Ćirić, L.J   +3 more
core  

Effects of verapamil and diltiazem on human platelet function

open access: yes, 1986
In this study the antiplatelet properties of two calcium channel blockers, verapamil and diltiazem, were evaluated. In 20 random aspirin-abstaining donors, both diltiazem and verapamil (0.01-10 microM) reduced epinephrine-induced aggregation [46 +/- 6% (
C. A. Fisher   +5 more
core   +1 more source

The Efficacy of Amlodipine and Diltiazem in Cyclosporine Dose Adjustment with Respect to Trough and 2-hour Concentrations in Kidney Transplant Patients [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2009
Background & Aims: Hypertension, hyperuricaemia and nephrotoxicity are some common side-effects of Cyclosporine A (CsA) treatment in renal transplant recipients. Previous studies suggest that Calcium Channel Blockers (CCB) can increase serum level of CsA
J Azmandiyan   +5 more
doaj  

Effects of diltiazem on hemodynamic variables and ventricular function in healthy horses

open access: yes, 2005
Quinidine is effective for treatment of atrial fibrillation (AF) in horses, but often accelerates ventricular response rate. Diltiazem effectively controls heart rate response to AF in other species. This investigation determined the effects of diltiazem
Schwarzwald, Colin C; https://orcid.org/   +2 more
core   +1 more source

Diltiazem hydrochloride with first order modified release

open access: yes, 2022
Diltiazem is a benzodiazepine derivative that actively blocks voltage-gated calcium channels in smooth muscle and the myocardium. Diltiazem hydrochloride was first approved by the FDA in 1982.
Kristín Káradóttir 1995-   +3 more
core  

Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole

open access: yesClinical Pharmacology: Advances and Applications, 2011
Chirag G Patel, Li Li, Suzette Girgis, David M Kornhauser, Ernest U Frevert, David W BoultonBristol-Myers Squibb, Princeton, NJ, USABackground: Many medicines, including several cholesterol-lowering agents (eg, lovastatin, simvastatin), antihypertensives
Patel C   +5 more
doaj  

Comparison of the metabolic and antioxidant effects of diltiazem and vitamin E on streptozotocin-diabetic rats

open access: yes, 2004
In this study, solitary and combined effects of vitamin E and the calcium-channel blocker diltiazem were investigated in streptozotocin (STZ)-induced diabetic rats. Thirty male Wistar albino rats, weighing approximately 200 g were used. Diabetes mellitus
ALBENIZ, Işıl   +4 more
core   +1 more source

Differential enhancement of postischemic segmental systolic thickening by diltiazem

open access: yes, 1990
Prolonged depression of segmental systolic thickening after brief coronary artery occlusion may result principally from events during reperfusion rather than during the ischemic interval.
Taylor, Anne L.   +5 more
core   +1 more source

Microbial enantioselective synthesis of a key intermediate for Diltiazem [PDF]

open access: yes
LAUREA MAGISTRALEOggetto della tesi è stata la produzione biocatalitica di un intermedio chiave per la sintesi del diltiazem, attraverso la riduzione del corrispondente precursore mediata da microorganismi.
Turpanova, Meruyert
core  

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