OBJETIVE: Antihypertensive therapy with thiazides decreases coronary events in elderly patients. However, the influence of diuretics on myocardial ischemia has not been fully investigated. The aim of this study was to compare the effect of chlorthalidone
João Batista Serro-Azul +9 more
doaj +1 more source
Rate-dependent and antiarrhythmic reentrant tachycardia (AVNRT) effects of simvastatin in isolated rabbit atrioventricular nodal model [PDF]
Background and purpose: Several previous studies have shown the direct and indirect effects of statins on supraventricular and ventricular arrhythmia. The purpose of the present study is to determine (1) whether Simvastatin modifies the rate-dependent ...
Alizadeh, A.M. +8 more
core
Catheter ablation vs. antiarrhythmic drug therapy in patients with symptomatic atrioventricular nodal re-entrant tachycardia: a randomized, controlled trial. [PDF]
Aims: To conduct a randomized trial in order to guide the optimum therapy of symptomatic atrioventricular nodal re-entrant tachycardia (AVNRT).
Camm, AJ +7 more
core +1 more source
Objective: This study aimed to show the effects of intra-operative diltiazem infusion on flow in arterial and venous grafts in coronary artery bypass graft surgery. Methods: Hundred fourty patients with a total of 361 grafts [205 (57%) arterial and 156 (
Ozan Erdem +6 more
doaj +1 more source
Background and Aim: Anal fissure is one of the common anorectal disorders that there are various therapies for it. The aim of this study is to evaluate the effect of Nitroglycerin plus Diltiazem vs either topical Diltiazem and Bethanechol alone in the ...
Baran Parhizkar +4 more
doaj
Antimicrobial activities of Diltiazem Hydrochloride: drug repurposing approach [PDF]
Background The growing concern of antibiotic-resistant microbial strains worldwide has prompted the need for alternative methods to combat microbial resistance.
Omar K. Alduaij +3 more
doaj +2 more sources
Role of nitric oxide on the electrophysiological properties of isolated rabbit atrioventricular node by extracellular field potential during atrial fibrillation [PDF]
Introduction: The aim of the present study was to determine direct effects of NO modulation on protective electrophysiological properties of atrioventricular node (AV node) in the experimental model of AF in rabbit.
Alizadeh, A.M. +10 more
core
BackgroundTacrolimus is widely used to treat pediatric nephrotic range proteinuria (NRP). Diltiazem, a CYP3A4/5 inhibitor, is often administered with tacrolimus, affecting its pharmacokinetic profile. The impact of this combination on tacrolimus exposure,
Qiaoling Yang +10 more
doaj +1 more source
Impacts of compound properties and sediment characteristics on the sorption behaviour of pharmaceuticals in aquatic systems [PDF]
Sorption is a key factor in determining the persistence, attenuation and bioavailability of sediment-associated contaminants. However, our understanding of the sorption behaviour of pharmaceuticals in sediments is poor. In this study, we investigated the
Al-Khazrajy, Omar S A +1 more
core +1 more source
The Efficacy of Diltiazem Gel on Diminution of Patients’ Complaints After Anal Surgery
<p><strong>Background and objectives</strong></p><p> Local pain and painful defecation are common patients’ complaints after anal surgery.
S.J Ashagh Hosseeyni
doaj

