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Antimicrobial activities of Diltiazem Hydrochloride: drug repurposing approach [PDF]
PeerJBackground The growing concern of antibiotic-resistant microbial strains worldwide has prompted the need for alternative methods to combat microbial resistance.
Omar K. Alduaij +3 more
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Indonesian Journal of Pharmacy, 2021 Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was ...
Lina Winarti +2 more
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Preparation of modified release diltiazem HCl capsule by complexation with ion exchange resin [PDF]
المجلة العراقية للصيدلة, 2011 Background: Diltiazem HCl is a calcium channel blocker drug used in the treatment of angina pectoris and hypertension. Objective: To prepare a sustained release diltiazem HCl capsule by complexation with polystyrene sulfonate strong cation exchange resin
Eman B.H. Al-Khedairy +2 more
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SIMULTANEOUS HPLC-UV QUANTIFICATION OF DILTIAZEM AND N-DEMETHYLDILTIAZEM IN HUMAN PLASMA [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2006 A simple and sensitive reversed phase high-performance liquidchromatographic method was developed for simultaneousquantification of diltiazem HCl and its major metabolite Ndemethyldiltiazemin human plasma.
S. Raza +3 more
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Journal of Pharmaceutical Analysis, 2020 An understanding of the thermodynamics of the complexation process utilized in sustaining drug release in clay matrices is of great importance. Several characterisation techniques as well as isothermal calorimetry were utilized in investigating the ...
Ana-Maria Totea +7 more
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Formulation and In-Vitro Evaluation of Mucoadhesive Diltiazem Hydrochloride Buccal Tablets
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2011 Mucoadhesive tablets for buccal administration of diltiazem hydrochloride were prepared as an alternative to available diltiazem HCl dosage forms. Two types of tablets were developed each containing two mucoadhesive components (hydroxypropylmethyl ...
Lubna A. Sabri
doaj +1 more source
Journal of Advanced Pharmaceutical Technology & Research, 2013 The aim of the present study was to develop controlled-release pellets of diltiazem HCl with ethyl cellulose and hydroxylpropyl methylcellulose phthalate as the release rate retarding polymers by fluid bed coating technique.
Mikkilineni Bhanu Prasad +4 more
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Kompleks Polielektrolit Kitosan-Xanthan sebagai Matriks Sediaan Mukoadhesif
Pharmaceutical Sciences and Research, 2017 Mucoadhesive dosage form is a pharmaceutical dosage form with prolonged gastric residence time which can increase bioavailability of drugs. An excipient with suitable swelling and bioadhesive characteristics plays important role to obtain good ...
Kurnia Sari Setio Putri +2 more
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Journal of Basic and Applied Research in Biomedicine, 2022 The use of natural polymers in the design of drug delivery formulation has received much attention due to their excellent biocompatibility and biodegradability.
Rohit Bhosale +2 more
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Acta Pharmaceutica, 2014 Eudragit E (EE)-sodium alginate (SA) polyelectrolyte complexes (PECs) were prepared at pH 4 and 5.8 using sodium alginate of high (SAH) and low viscosity (SAL).
Yusif Rehab Mohammad +2 more
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