Microencapsulation by Spray Coagulation of Diltiazem HCl in Calcium Alginate-Coated Chitosan [PDF]
AAPS PharmSciTech, 2008 The aim of this work was to develop a procedure for encapsulation of diltiazem HCl by spray coagulation. Factors affecting the formulations such as the effect of NaCl on the solubility of diltiazem in alginate solution, surface tension, pH, viscosity of the coagulation medium, and the effect of drug load on drug release were studied.
Cristian Tapia, Mehrdad Yazdani-Pedram
exaly +8 more sources
Antiviral Activity of Diltiazem HCl Against Pseudorabies Virus Infection In Vitro [PDF]
Veterinary SciencesPseudorabies virus (PRV) is a highly pathogenic agent that adversely impacts swine populations, leading to considerable economic losses within the Chinese pig industry.
Mengting Zuo +11 more
doaj +3 more sources
Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer In Diltiazem Hydrochloride Mucoadhesive Buccal Film [PDF]
Indonesian Journal of Pharmacy, 2021 Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was ...
Lina Winarti +2 more
doaj +4 more sources
Biodegradable microparticulate drug delivery system of diltiazem HCl [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2012 The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time.
Manish Kumar Gupta +2 more
doaj +4 more sources
Antimicrobial activities of Diltiazem Hydrochloride: drug repurposing approach [PDF]
PeerJBackground The growing concern of antibiotic-resistant microbial strains worldwide has prompted the need for alternative methods to combat microbial resistance.
Omar K. Alduaij +3 more
doaj +3 more sources
An Optimasi Polivinil Pirolidon dan Kitosan dalam Sediaan Mucoadhesive Buccal Film Diltiazem HCl [PDF]
Pustaka Kesehatan, 2020 Diltiazem HCl adalah golongan benzoatiazepin penghambat kanal kalsium (calcium channel blocker) yang digunakan dalam pengobatan angina pektoris, aritmia, dan hipertensi. Diltiazem HCl mengalami first pass metabolism di hati, waktu paruh yang pendek yakni
Novita, Ulfia Dwi +2 more
core +3 more sources
Sodium Alginate - Gelatin Cross-Linked Microspheres for Releasing Diltiazem Hcl
Science Journal of University of Zakho, 2016 Semi-interpenetrating polymer network (semi-IPN) microspheres of Sodium alginate (NaAlg) and Gelatin were prepared and cross-linked with glutaraldehyde by using emulsification/solvent-evaporation method to deliver Diltiazem HCl as a model of drug ...
Alarqam Z. Tareq, Mohammed S. Hussein
doaj +2 more sources
An investigation into the stabilization of diltiazem HCl release from matrices made from aged polyox powders. [PDF]
AAPS PharmSciTech, 2013 Matrices containing PEO fail to provide stable drug release profiles when stored at elevated temperatures for a period of time. The present study aims to stabilize diltiazem HCl release from matrices made from various molecular weights of polyox powders.
Shojaee S +4 more
europepmc +4 more sources
Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. [PDF]
J Young Pharm, 2010 The matrix tablets of diltiazem hydrochloride were prepared by direct compression using hydroxypropyl methyl cellulose (HPMC) and various amounts (2.5%, 5.0%, 10% and 20%) of citric acid, malic acid and succinic acid. The characterization of physical mixture of drug and organic acids was performed by Infra-red spectroscopy.
Sateesha S, Rajamma A, Narode M, Vyas B.
europepmc +4 more sources
Development and release mechanism of diltiazem HCl prolonged release matrix tablets [PDF]
Drug Delivery, 2009 A coated matrix tablet formulation has been used to develop controlled release diltiazem HCl (DIL) tablets. The developed drug delivery system provided prolonged drug release rates over a defined period of time. DIL tablets prepared using dry mixing and direct compression and the core consisted of hydrophilic and hydrophobic polymers such as ...
Dionysios Douroumis
exaly +3 more sources