Results 31 to 40 of about 4,480 (170)

Kompleks Polielektrolit Kitosan-Xanthan sebagai Matriks Sediaan Mukoadhesif

open access: yesPharmaceutical Sciences and Research, 2017
Mucoadhesive dosage form is a pharmaceutical dosage form with prolonged gastric residence time which can increase bioavailability of drugs. An excipient with suitable swelling and bioadhesive characteristics plays important role to obtain good ...
Kurnia Sari Setio Putri   +2 more
doaj   +1 more source

Formulation and Evaluation of Chitosan-Gellan Beads as Controlled Drug Delivery System of Antihypertensive Drug

open access: yesJournal of Basic and Applied Research in Biomedicine, 2022
The use of natural polymers in the design of drug delivery formulation has received much attention due to their excellent biocompatibility and biodegradability.
Rohit Bhosale   +2 more
doaj   +2 more sources

Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules [PDF]

open access: yes, 2018
Understanding the molecular mechanisms regulating cardiac cell proliferation during the embryonic, fetal and adult life holds a paramount importance in view of developing innovative strategies aimed at inducing myocardial regeneration after cardiac ...
Torrini, Consuelo
core   +1 more source

Some variables affecting the characteristics of Eudragit E-sodium alginate polyelectrolyte complex as a tablet matrix for diltiazem hydrochloride

open access: yesActa Pharmaceutica, 2014
Eudragit E (EE)-sodium alginate (SA) polyelectrolyte complexes (PECs) were prepared at pH 4 and 5.8 using sodium alginate of high (SAH) and low viscosity (SAL).
Yusif Rehab Mohammad   +2 more
doaj   +1 more source

In vivo Assessment of Diltiazem HCl Immobilized Co-polymeric pH Sensitive Microgels

open access: yesFRONTIERS IN CHEMICAL SCIENCES, 2023
Novel stimuli responsive coplymeric (2-ethyl hexyl acrylate -co- itaconic acid diltiazem HCl loaded microgels were fabricated and characterized successfully to reduce the degradation of drugs in acidic pH of stomach resulting in reduced bioavailability to minimize dosing frequency and enhance patient compliance.
Rabia Razzaq   +3 more
openaire   +1 more source

Optimasi Hydroxypropyl Methylcellulose dan Chitosan pada Tablet Floating-Mucoadhesive Diltiazem Hidroklorida Menggunakan Desain Faktorial [PDF]

open access: yes, 2020
Diltiazem HCl is one of the drugs used for hypertension treatment. It requires frequent dosing, which is why diltiazem HCl needs to be formulated into preparations using a controlled release drug delivery system.
Sari, Lusia Oktora Ruma Kumala   +2 more
core   +2 more sources

Development and Validation of Novel Analytical Method for Estimation of Diltiazem HCL

open access: yesInternational Journal Of Pharmaceutical And Bio-Medical Science, 2023
A novel, simple, accurate and precise Zero order derivative spectroscopic method was developed and validated for the estimation of Diltiazem HCl in bulk and Pharmaceutical dosage forms and has an absorption maximum at 193 nm in 0.05N Sulphuric acid. The Linearity was found to be in the concentration range of 3-18 μg/ml and the correlation coefficient ...
M, Pooja, Chaithra CN, Rajasekaran, S.
openaire   +1 more source

The influence of fillers on theophylline release from clay matrices [PDF]

open access: yes, 2015
: The objectives of this study were to investigate the suitability of magnesium aluminium silicate (MAS) (Veegum®) to control drug release of a model drug, theophylline, from tablet matrices.
Adebisi, Adeola O.   +2 more
core   +1 more source

A novel approach to crystallisation of nanodispersible microparticles by spray drying for improved tabletability [PDF]

open access: yes, 2012
YesHigh-dose API powders which are to be tableted by direct compression should have high compactibility and compressibility. This note reports on a novel approach to the manufacture of crystalline powders intended for direct compaction with improved ...
Adamczyk, B.   +4 more
core   +1 more source

Development and evaluation of microporous osmotic tablets of diltiazem hydrochloride

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2012
Microporous osmotic tablet of diltiazem hydrochloride was developed for colon targeting. These prepared microporous osmotic pump tablet did not require laser drilling to deliver the drug to the specific site of action.
Afifa Bathool   +5 more
doaj   +1 more source

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