Sodium Alginate - Gelatin Cross-Linked Microspheres for Releasing Diltiazem Hcl [PDF]
Science Journal of University of Zakho, 2016 Semi-interpenetrating polymer network (semi-IPN) microspheres of Sodium alginate (NaAlg) and Gelatin were prepared and cross-linked with glutaraldehyde by using emulsification/solvent-evaporation method to deliver Diltiazem HCl as a model of drug ...
Alarqam Z. Tareq, Mohammed S. Hussein
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Biodegradable microparticulate drug delivery system of diltiazem HCl [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2012 The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time.
Manish Kumar Gupta +2 more
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The effect of pH and Polymer type on Release of Diltiazem HCl from hydrophilic matrices
Journal of Mazandaran University of Medical Sciences, 2007 Background and Purpose: Oral administrations have been used for many years as a main method comparing to other methods. Sustained release techniques have been a great interest recently.
J. Akbari, Ph.D. +3 more
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An investigation into the stabilization of diltiazem HCl release from matrices made from aged polyox powders. [PDF]
AAPS PharmSciTech, 2013 . Matrices containing PEO fail to provide stable drug release profiles when stored at elevated temperatures for a period of time. The present study aims to stabilize diltiazem HCl release from matrices made from various molecular weights of polyox ...
Shojaee S +4 more
europepmc +2 more sources
Preparation of modified release diltiazem HCl capsule by complexation with ion exchange resin [PDF]
المجلة العراقية للصيدلة, 2011 Background: Diltiazem HCl is a calcium channel blocker drug used in the treatment of angina pectoris and hypertension. Objective: To prepare a sustained release diltiazem HCl capsule by complexation with polystyrene sulfonate strong cation exchange resin
Eman B.H. Al-Khedairy +2 more
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An Optimasi Polivinil Pirolidon dan Kitosan dalam Sediaan Mucoadhesive Buccal Film Diltiazem HCl [PDF]
, 2020 Diltiazem HCl adalah golongan benzoatiazepin penghambat kanal kalsium (calcium channel blocker) yang digunakan dalam pengobatan angina pektoris, aritmia, dan hipertensi. Diltiazem HCl mengalami first pass metabolism di hati, waktu paruh yang pendek yakni
Rosyidi, Viddy Agustian +2 more
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SIMULTANEOUS HPLC-UV QUANTIFICATION OF DILTIAZEM AND N-DEMETHYLDILTIAZEM IN HUMAN PLASMA [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2006 A simple and sensitive reversed phase high-performance liquidchromatographic method was developed for simultaneousquantification of diltiazem HCl and its major metabolite Ndemethyldiltiazemin human plasma.
S. Raza +3 more
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Journal of Pharmaceutical Analysis, 2020 An understanding of the thermodynamics of the complexation process utilized in sustaining drug release in clay matrices is of great importance. Several characterisation techniques as well as isothermal calorimetry were utilized in investigating the ...
Ana-Maria Totea +7 more
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DESIGN AND EVALUATION OF BILAYER FLOATING TABLETS OF DILTIAZEM HCL [PDF]
, 2017 The present investigation concerns design and evaluation of bilayer floating tablets of Diltiazem HCl Diltiazem HCl is Class I drug, though its reported bioavailability is only 40 %. It is having very short half life of 3 to 4 hrs.
Shaikh Siraj Nawaj*, Md. ZuberPatel,,G. J. Khan, Patel M Siddik,ZakirShaikh
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Optimasi Hidroksipropil Metilselulosa dan Polivinil Pirolidon dalam Sediaan Mucoadhesive Buccal Film Diltiazem Hidroklorida [PDF]
, 2021 Diltiazem HCl is a class of benzodiazepine calcium channel blockers used to treat angina pectoris, arrhythmias, and hypertension. Diltiazem HCl improves first-pass metabolism, a short half time of 3-5 hours, and bioavailability of diltiazem for oral ...
Wicaksono, Yudi +2 more
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