Design & Evaluation of Pulsatile Drug Delivery of Diltiazem Hcl
Oral controlled drug delivery systems represent the most popular form of controlled drug delivery systems for the obvious advantages of oral route of drug administration.
BHUKYA NAGARAJU - +2 more
openaire +1 more source
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
Clinical Experience with Diltiazem in the Treatment of Cardiovascular Diseases [PDF]
Cardiovascular diseases are the leading cause of death in the world. Coronary artery diseases, atrial fibrillation or hypertensive heart disease, are among the most important cardiovascular disorders. Hypertension represents a significant risk factor for
Alejandro de la Sierra +5 more
core +4 more sources
Formulation and In-Vitro Evaluation of Mucoadhesive Diltiazem Hydrochloride Buccal Tablets
Mucoadhesive tablets for buccal administration of diltiazem hydrochloride were prepared as an alternative to available diltiazem HCl dosage forms. Two types of tablets were developed each containing two mucoadhesive components (hydroxypropylmethyl ...
Lubna A. Sabri
doaj +1 more source
Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi +59 more
core +1 more source
Comparative effectiveness of monotherapies and combination therapies for patients with hypertension: protocol for a systematic review with network meta-analyses [PDF]
BACKGROUND: Hypertension has been cited as the most common attributable risk factor for death worldwide, and in Canada more than one of every five adults had this diagnosis in 2007.
Andrea Tricco +12 more
core +1 more source
The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function [PDF]
High blood pressure (BP) is the most common cardiovascular risk factor worldwide and a major contributor to heart disease and stroke. We previously discovered a BP-associated missense SNP (single nucleotide polymorphism)-rs2272996-in the gene encoding ...
Bandyopadhyay, Anupam +14 more
core +7 more sources
The aim of the present study was to develop controlled-release pellets of diltiazem HCl with ethyl cellulose and hydroxylpropyl methylcellulose phthalate as the release rate retarding polymers by fluid bed coating technique.
Mikkilineni Bhanu Prasad +4 more
doaj +1 more source
DILTIAZEM HCL: EVALUATION OF ITS PRESENCE IN BANGLADESH
Diltiazem hydrochloride is a calcium channel blocker used for the treatment of chronic stable angina pectoris as well as for angina pectoris caused by a coronary arterial spasm and systemic hypertension. In spite of these life - saving health benefits, this drug molecule has been found to be losing its market value in Bangladesh du e its side effects ...
Rahman Kabir Eva, Samin Huq
openaire +1 more source

