Results 21 to 30 of about 34,830 (218)
PLoS ONE, 2018 BackgroundArterial graft spasm is a severe complication after coronary artery bypass graft (CABG). Among numerous potential antispasmodic agents, systemic application of diltiazem and nitroglycerin had been investigated most frequently over the past ...
Yirui Hu +8 more
doaj +1 more source
Asian Journal of Surgery, 2018 Summary: Background: Hemorrhoidectomy is commonly associated with postoperative pain. Calcium channel blockers are known to cause relaxation of gastrointestinal smooth muscle and oral diltiazem has also been shown to reduce the resting anal pressure ...
Yan-Jiun Huang +4 more
doaj +1 more source
International Journal of Cardiology: Heart & Vasculature, 2021 Background: Amiodarone and diltiazem are commonly recommended cardiovascular medications for use in atrial fibrillation (AF) patients. They are known to have drug-drug interactions (DDIs) with direct oral anticoagulants (DOACs).
Mohammed Shurrab +8 more
doaj +1 more source
Clinical Experience with Diltiazem in the Treatment of Cardiovascular Diseases [PDF]
, 2016 Cardiovascular diseases are the leading cause of death in the world. Coronary artery diseases, atrial fibrillation or hypertensive heart disease, are among the most important cardiovascular disorders. Hypertension represents a significant risk factor for
Alejandro de la Sierra +5 more
core +4 more sources
PLoS ONE, 2020 Background Beta-blockers are often not the preferred treatment for patients with vasospastic angina. However, nebivolol, beta-blocker with nitric oxide-releasing effect, could theoretically improve coronary vasospasm.
Hyungdon Kook +6 more
doaj +2 more sources
Combined Effects of Benidipine and Diltiazem in a Rat Model of Experimental Angina
Journal of Pharmacological Sciences, 2004 We examined the combined effects of the calcium channel blockers 1,4-dihydropyridine (benidipine) and benzothiazepine (diltiazem) on vasopressin-induced myocardial ischemia in anesthetized rats, an experimental model of angina. Benidipine (3, 10 μg/kg, i.
Kozo Yao, Shiro Shirakura
doaj +1 more source
Study of basis-transmitter influence on biopharmaceutical properties of diltiazem nasal dosage form
Zaporožskij Medicinskij Žurnal, 2013 It is set that the type of basis-transmitter has an influence on release of diltiazem from intranasal ointments. Variance analysis of researches results showed that transmitter on the basis of methylcellulose glycerogel provides optimal diltiazem ...
V. V. Gladyshev +2 more
doaj +1 more source
Cellular Physiology and Biochemistry, 2016 Background/Aims: In this study, we examined whether the combination of hyperbaric oxygen (HBO) and diltiazem therapy provided a cardioprotective effect on myocardial ischemia-reperfusion injury (MIRI) rat model. Methods: Sixty healthy Sprague-Dawley rats
Chunxia Chen +5 more
doaj +1 more source
Photoinduced Removal of Nifedipine Reveals Mechanisms of Calcium Antagonist Action on Single Heart Cells [PDF]
, 1985 The currents through voltage-activated calcium channels in heart cell membranes are suppressed by dihydropyridine calcium antagonists such as nifedipine.
Gurney, Alison M. +2 more
core +2 more sources
Brazilian Oral Research, 2005 The administration of calcium channel blockers has been associated with gingival overgrowth. However, there are few studies in humans or animals that evaluated the effect of diltiazem on gingival tissues.
Fernanda de Oliveira Bello Corrêa +4 more
doaj +1 more source