Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia +17 more
core +1 more source
Background Diltiazem stands out as one of the front-line drugs administered in the emergency department to achieve acute rate control in patients suffering from atrial fibrillation with rapid Ventricular Response.
Mehmet Uluturk +9 more
doaj +1 more source
Older patients' prescriptions screening in the community pharmacy: development of the Ghent Older People's Prescriptions community Pharmacy Screening (GheOP3S) tool [PDF]
Background: Ageing of the population often leads to polypharmacy. Consequently, potentially inappropriate prescribing (PIP) becomes more frequent. Systematic screening for PIP in older patients in primary care could yield a large improvement in health ...
Boussery, Koen +5 more
core +2 more sources
Structural Basis for Diltiazem Block of a Voltage-Gated Ca2+ Channel
Diltiazem is a widely prescribed Ca2+ antagonist drug for cardiac arrhythmia, hypertension, and angina pectoris. Using the ancestral CaV channel construct CaVAb as a molecular model for X-ray crystallographic analysis, we show here that diltiazem targets
Lin Tang +4 more
semanticscholar +1 more source
İn this study we investigated the effects of diltiazem alone or in combination with lithium on some behavioral param eters and serum sodium potassium and calcium levels in rats. 36 W istar Albino rats were divided into 4 groups and treated as follows, C
Göksel Şener +2 more
doaj
Intravenous Continuous Infusion vs. Oral Immediate-release Diltiazem for Acute Heart Rate Control
Introduction: Atrial fibrillation (AF) is a common diagnosis of patients presenting to the emergency department (ED). Intravenous (IV) diltiazem bolus is often the initial drug of choice for acute management of AF with rapid ventricular response (RVR ...
Kimberly N. Means +2 more
doaj +1 more source
Ca2+ transients are not required as signals for long-term neurite outgrowth from cultured sympathetic neurons [PDF]
A method for clamping cytosolic free Ca2+ ([Ca2+]i) in cultures of rat sympathetic neurons at or below resting levels for several days was devised to determine whether Ca2+ signals are required for neurite outgrowth from neurons that depend on Nerve ...
Murrell, R D +3 more
core +2 more sources
A Wireless Power Transfer Based Implantable ECG Monitoring Device [PDF]
Implantable medical devices (IMDs) enable patients to monitor their health anytime and receive treatment anywhere. However, due to the limited capacity of a battery, their functionalities are restricted, and the devices may not achieve their intended ...
Dongwook Kim +6 more
core +1 more source
Randomized clinical trial with topical diltiazem for post-hemorrhoidectomy wound healing
Anal sphincter spasm contributes to the delay in surgical wound healing after hemorrhoidectomy. A prospective, experimental, randomized, double-blind trial was conducted on two groups of patients that underwent closed hemorrhoidectomy.
U. Rodríguez-Wong +2 more
doaj +1 more source
Non-adherence to cardiovascular pharmacotherapy in Iraq assessed using 8-items Morisky questionnaire and analysis of dried blood spot samples [PDF]
open access journalThe study evaluated the non-adherence to selected cardiovascular medications, atenolol, atorvastatin, bisoprolol, diltiazem, lisinopril, simvastatin and valsartan in Iraqi patients by applying a standardized Morisky questionnaire (8 ...
Alalaqi, Ahmed +3 more
core +1 more source

