Results 31 to 40 of about 19,064 (180)

Diltiazem-cyclosporin pharmacokinetic interaction - dose-response relationship.

open access: yes, 1997
Aims: To study the dose-response relationship of the pharmacokinetic interaction between diltiazem and cyclosporin in kidney transplant recipients. Methods: Eight stable kidney transplant recipients maintained on cyclosporin but not taking diltiazem ...
Mathew, T., Morris, R., Jones, T.
core   +1 more source

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao   +8 more
wiley   +1 more source

Considerations for drug trials in hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant   +17 more
wiley   +1 more source

Rate control with intravenous diltiazem, verapamil, and metoprolol in acute atrial fibrillation with rapid ventricular rate

open access: yesSAGE Open Medicine, 2021
Introduction: Diltiazem is a preferred agent for rate control in atrial fibrillation due to its quick onset, minimal side effects, and low cost. Due to its intermittent national shortage since February 2018, the utilization of intravenous metoprolol and ...
Tia Medeiros   +4 more
doaj   +1 more source

An Expired Non-Toxic Diltiazem Hydrochloride as Corrosion Inhibitor for Cu in Nitric Acid Medium

open access: yesInternational Journal of Electrochemical Science, 2017
The corrosion inhibition of Cu in 1 M HNO3 solution by expired Diltiazem Hydrochloride (HD) has been tested by Tafel polarization, electrical frequency modulation, electrical impedance spectroscopy, and mass loss method. The Diltiazem Hydrochloride gives
A.S. Fouda   +3 more
doaj   +1 more source

The Effect of Smearing Tracheal Tube Cuff with Diltiazem Gel on Cardiovascular Changes in Patients Underwent Laparoscopic Cholecystectomy Surgery: A Clinical Trial Study

open access: yesمجله دانشکده پزشکی اصفهان, 2020
Background: Tracheal intubation can result in extensive changes in heart rate and blood pressure. The aim of this study was to investigate the effect of smearing tracheal tube cuff with diltiazem gel on cardiovascular changes in patients who underwent ...
Javad Amini-saman   +4 more
doaj   +1 more source

Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer In Diltiazem Hydrochloride Mucoadhesive Buccal Film

open access: yesIndonesian Journal of Pharmacy, 2021
Diltiazem hydrochloride (HCl) is a category of calcium channel blocker used as an antihypertensive agent. Diltiazem HCl is a low bioavailable drug due to high first-pass metabolism and a short half-life (3-5 hours); hence mucoadhesive buccal film was ...
Lina Winarti   +2 more
doaj   +1 more source

Revisiting the Association Between Calcium Channel Blockers and Parkinson's Disease in the E3N Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard   +9 more
wiley   +1 more source

Effects of Intravenous Diltiazem on Supraventricular Tachyarrhythmias [PDF]

open access: yes, 1991
The effects of intravenous diltiazem on supraventricular tachyarrhythmias were studied in 16 patients : 6 with paroxysmal supraventricular tachycardia using an accessory pathway retrogradely, 6 with atrial fibrillation, 3 with atrial flutter and 1 with ...
Mori, Hideki   +4 more
core   +1 more source

Effect of the human therapeutic drug diltiazem on the haematological parameters, histology and selected enzymatic activities of rainbow trout Oncorhynchus mykiss.

open access: yes, 2016
Diltiazem is a pharmaceutical belonging to a group of calcium channel blockers (CCB) that is widely used in the treatment of angina pectoris and hypertension.
Kolarova, Jitka   +7 more
core   +1 more source

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