Results 21 to 30 of about 19,064 (180)
Combined Effects of Benidipine and Diltiazem in a Rat Model of Experimental Angina
Journal of Pharmacological Sciences, 2004 We examined the combined effects of the calcium channel blockers 1,4-dihydropyridine (benidipine) and benzothiazepine (diltiazem) on vasopressin-induced myocardial ischemia in anesthetized rats, an experimental model of angina. Benidipine (3, 10 μg/kg, i.
Kozo Yao, Shiro Shirakura
doaj +1 more source
PLoS ONE, 2020 Background Beta-blockers are often not the preferred treatment for patients with vasospastic angina. However, nebivolol, beta-blocker with nitric oxide-releasing effect, could theoretically improve coronary vasospasm.
Hyungdon Kook +6 more
doaj +2 more sources
Asian Journal of Surgery, 2018 Summary: Background: Hemorrhoidectomy is commonly associated with postoperative pain. Calcium channel blockers are known to cause relaxation of gastrointestinal smooth muscle and oral diltiazem has also been shown to reduce the resting anal pressure ...
Yan-Jiun Huang +4 more
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Study of basis-transmitter influence on biopharmaceutical properties of diltiazem nasal dosage form
Zaporožskij Medicinskij Žurnal, 2013 It is set that the type of basis-transmitter has an influence on release of diltiazem from intranasal ointments. Variance analysis of researches results showed that transmitter on the basis of methylcellulose glycerogel provides optimal diltiazem ...
V. V. Gladyshev +2 more
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Diltiazem inhibits hKv1.5 and Kv4.3 currents at therapeutic concentrations
, 2004 Objective: In the present study we examined the effects of diltiazem, an L-type Ca(2+) channel blocker widely used for the control of the ventricular rate in patients with supraventricular arrhythmias, on hKv1.5 and Kv4.3 channels that generate the ...
Tamargo Menéndez, Juan +5 more
core +1 more source
Cellular Physiology and Biochemistry, 2016 Background/Aims: In this study, we examined whether the combination of hyperbaric oxygen (HBO) and diltiazem therapy provided a cardioprotective effect on myocardial ischemia-reperfusion injury (MIRI) rat model. Methods: Sixty healthy Sprague-Dawley rats
Chunxia Chen +5 more
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Brazilian Oral Research, 2005 The administration of calcium channel blockers has been associated with gingival overgrowth. However, there are few studies in humans or animals that evaluated the effect of diltiazem on gingival tissues.
Fernanda de Oliveira Bello Corrêa +4 more
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, 1998 To assess the contribution of its metabolites to the antihypertensive effects of diltiazem, a previously established rabbit model has been used to compare the pharmacokinetics and haemodynamic effects of the drug with those of its major metabolites ...
Joe D Z Feng +2 more
core +1 more source
Revista de Gastroenterología de México, 2019 Resumen: El espasmo del esfínter anal contribuye al retardo en la cicatrización de las heridas quirúrgicas después de una hemorroidectomía. Se realizó un estudio aleatorizado, prospectivo, experimental, doble ciego, de dos grupos de pacientes en los que ...
U. Rodríguez-Wong +2 more
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Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Index of microcirculatory resistance (IMR) is a cutting‐edge, wire‐based tool that advances the capability assessment of coronary microvascular function. By utilizing distal coronary pressure and mean transit time under maximal hyperemia, IMR delivers consistent, reproducible insights into the microvasculature's dynamic health.
Joanna Sohn +10 more
wiley +1 more source