Results 21 to 30 of about 20,818 (203)

Randomized clinical trial with topical diltiazem for post-hemorrhoidectomy wound healing

open access: yesRevista de Gastroenterología de México (English Edition), 2019
Anal sphincter spasm contributes to the delay in surgical wound healing after hemorrhoidectomy. A prospective, experimental, randomized, double-blind trial was conducted on two groups of patients that underwent closed hemorrhoidectomy.
U. Rodríguez-Wong   +2 more
doaj   +1 more source

Prescribing of two potentially interacting cardiovascular medications in atrial fibrillation patients on direct oral anticoagulants

open access: yesInternational Journal of Cardiology: Heart & Vasculature, 2021
Background: Amiodarone and diltiazem are commonly recommended cardiovascular medications for use in atrial fibrillation (AF) patients. They are known to have drug-drug interactions (DDIs) with direct oral anticoagulants (DOACs).
Mohammed Shurrab   +8 more
doaj   +1 more source

Topical diltiazem ointment in post-hemorrhoidectomy pain relief: A meta-analysis of randomized controlled trials

open access: yesAsian Journal of Surgery, 2018
Summary: Background: Hemorrhoidectomy is commonly associated with postoperative pain. Calcium channel blockers are known to cause relaxation of gastrointestinal smooth muscle and oral diltiazem has also been shown to reduce the resting anal pressure ...
Yan-Jiun Huang   +4 more
doaj   +1 more source

Study of basis-transmitter influence on biopharmaceutical properties of diltiazem nasal dosage form

open access: yesZaporožskij Medicinskij Žurnal, 2013
It is set that the type of basis-transmitter has an influence on release of diltiazem from intranasal ointments. Variance analysis of researches results showed that transmitter on the basis of methylcellulose glycerogel provides optimal diltiazem ...
V. V. Gladyshev   +2 more
doaj   +1 more source

Comparison of nebivolol versus diltiazem in improving coronary artery spasm and quality of life in patients with hypertension and vasospastic angina: A prospective, randomized, double-blind pilot study

open access: yesPLoS ONE, 2020
Background Beta-blockers are often not the preferred treatment for patients with vasospastic angina. However, nebivolol, beta-blocker with nitric oxide-releasing effect, could theoretically improve coronary vasospasm.
Hyungdon Kook   +6 more
doaj   +2 more sources

Combined Effects of Benidipine and Diltiazem in a Rat Model of Experimental Angina

open access: yesJournal of Pharmacological Sciences, 2004
We examined the combined effects of the calcium channel blockers 1,4-dihydropyridine (benidipine) and benzothiazepine (diltiazem) on vasopressin-induced myocardial ischemia in anesthetized rats, an experimental model of angina. Benidipine (3, 10 μg/kg, i.
Kozo Yao, Shiro Shirakura
doaj   +1 more source

Diltiazem inhibits hKv1.5 and Kv4.3 currents at therapeutic concentrations

open access: yes, 2004
Objective: In the present study we examined the effects of diltiazem, an L-type Ca(2+) channel blocker widely used for the control of the ventricular rate in patients with supraventricular arrhythmias, on hKv1.5 and Kv4.3 channels that generate the ...
Tamargo Menéndez, Juan   +5 more
core   +1 more source

Effect of the human therapeutic drug diltiazem on the haematological parameters, histology and selected enzymatic activities of rainbow trout Oncorhynchus mykiss. [PDF]

open access: yes, 2016
Diltiazem is a pharmaceutical belonging to a group of calcium channel blockers (CCB) that is widely used in the treatment of angina pectoris and hypertension.
Kolarova, Jitka   +7 more
core   +1 more source

Diltiazem did not induce gingival overgrowth in rats: a clinical, histological and histometric analysis Diltiazem não induziu crescimento gengival em ratos: análise clínica, histológica e histométrica

open access: yesBrazilian Oral Research, 2005
The administration of calcium channel blockers has been associated with gingival overgrowth. However, there are few studies in humans or animals that evaluated the effect of diltiazem on gingival tissues.
Fernanda de Oliveira Bello Corrêa   +4 more
doaj   +1 more source

Ensayo clínico aleatorizado con diltiazem tópico para la cicatrización de heridas posthemorroidectomía

open access: yesRevista de Gastroenterología de México, 2019
Resumen: El espasmo del esfínter anal contribuye al retardo en la cicatrización de las heridas quirúrgicas después de una hemorroidectomía. Se realizó un estudio aleatorizado, prospectivo, experimental, doble ciego, de dos grupos de pacientes en los que ...
U. Rodríguez-Wong   +2 more
doaj   +1 more source

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