Results 31 to 40 of about 55,609 (295)
PLoS ONE, 2018 BackgroundArterial graft spasm is a severe complication after coronary artery bypass graft (CABG). Among numerous potential antispasmodic agents, systemic application of diltiazem and nitroglycerin had been investigated most frequently over the past ...
Yirui Hu +8 more
doaj +1 more source
Pharmacology Research & Perspectives, 2018 This study investigated the protective effects of carvedilol alone and coadministered with prednisolone and diltiazem on doxorubicin (DOX) and 5‐fluorouracil (5‐FU)‐induced toxicity. Each of 2 pools of 70 female rats were randomly allotted into 10 groups
A. Akindele +4 more
semanticscholar +1 more source
Otology and Neurotology, 2019 HYPOTHESIS Local administration of the calcium-channel blocker (CCB), diltiazem, via intratympanic (IT) chitosan-glycerophosphate (CGP) hydrogel will protect against cisplatin-induced ototoxicity. BACKGROUND Cisplatin induces calcium-mediated apoptosis
James G. Naples +4 more
semanticscholar +1 more source
International Journal of Cardiology: Heart & Vasculature, 2021 Background: Amiodarone and diltiazem are commonly recommended cardiovascular medications for use in atrial fibrillation (AF) patients. They are known to have drug-drug interactions (DDIs) with direct oral anticoagulants (DOACs).
Mohammed Shurrab +8 more
doaj +1 more source
The Annals of Pharmacotherapy, 2018 Background: It is unknown whether diltiazem, a moderate cytochrome P450 enzyme (CYP3A4) and P-glycoprotein (P-gp) inhibitor, increases the incidence of bleeding events in combination with rivaroxaban, a CYP3A4 and P-gp substrate.
J. Bartlett +5 more
semanticscholar +1 more source
Asian Journal of Surgery, 2018 Summary: Background: Hemorrhoidectomy is commonly associated with postoperative pain. Calcium channel blockers are known to cause relaxation of gastrointestinal smooth muscle and oral diltiazem has also been shown to reduce the resting anal pressure ...
Yan-Jiun Huang +4 more
doaj +1 more source
D-cis-Diltiazem Can Produce Oxidative Stress in Healthy Depolarized Rods In Vivo
Investigative Ophthalmology and Visual Science, 2018 Purpose New perspectives are needed to understand decades of contradictory reports on the neuroprotective effects of the Cav1.2 L-type calcium channel blocker d-cis-diltiazem in retinitis pigmentosa (RP) models.
B. Berkowitz +10 more
semanticscholar +1 more source
Study of basis-transmitter influence on biopharmaceutical properties of diltiazem nasal dosage form
Zaporožskij Medicinskij Žurnal, 2013 It is set that the type of basis-transmitter has an influence on release of diltiazem from intranasal ointments. Variance analysis of researches results showed that transmitter on the basis of methylcellulose glycerogel provides optimal diltiazem ...
V. V. Gladyshev +2 more
doaj +1 more source
Brazilian Oral Research, 2005 The administration of calcium channel blockers has been associated with gingival overgrowth. However, there are few studies in humans or animals that evaluated the effect of diltiazem on gingival tissues.
Fernanda de Oliveira Bello Corrêa +4 more
doaj +1 more source
Revista de Gastroenterología de México, 2019 Resumen: El espasmo del esfínter anal contribuye al retardo en la cicatrización de las heridas quirúrgicas después de una hemorroidectomía. Se realizó un estudio aleatorizado, prospectivo, experimental, doble ciego, de dos grupos de pacientes en los que ...
U. Rodríguez-Wong +2 more
doaj +1 more source