Drug Delivery, 2017 Diltiazem hydrochloride (DTZ) is a calcium channel antagonist depicted by extensive first pass metabolism and low oral bioavailability. The aim of this work was to develop niosomes for potential nasal delivery of DTZ.
H. O. Ammar +3 more
doaj +1 more source
Asian Journal of Pharmaceutical Sciences, 2014 In this investigation, time-released monolithic osmotic pump (TMOP) tablets containing diltiazem hydrochloride (DIL) were prepared on the basis of osmotic pumping mechanism.
Tiegang Xin +7 more
doaj +1 more source
Hydrolytic stability of diltiazem in the presence of chosen polymers - Poloxamer 407 and Ammonio Metacrylate Copolymer Type B (Eudragit RS): а preliminary study [PDF]
, 2019 Introduction: The hydrolytic stability of the calcium channel blocker representative diltiazem hydrochloride in the presence of different polymeric entourage was quantitatively assessed using HPLC.Aim: The experiment was performed in order to establish ...
Ivanova, Nadezhda Antonova +2 more
core +2 more sources
Frontiers in Cellular and Infection MicrobiologyBackgroundThe flavivirus Duck Tembusu virus (DTMUV) exhibits high pathogenicity and transmissibility, posing a severe threat to the poultry industry in China and Southeast Asia.
Ziding Yu +26 more
doaj +1 more source
The evaluation of Eudragit microcapsules manufactured by solvent evaporation using USP Apparatus 1 [PDF]
, 2009 The objectives of this study were to prepare microcapsules containing verapamil and propranolol and to evaluate the kinetics and mechanism of drug release from the microcapsules using USP Apparatus 1. The effects of polymer concentration and polymer type
Haidula, H +4 more
core +2 more sources
Optimasi Tepung Lidah Buaya (Aloe Vera L.) Dan Carbopol 934p Sebagai Mucoadhesive Agent Pada Sediaan Mikrogranul Ranitidin Hcl Secara Simplex Lattice Design [PDF]
, 2017 Ranitidin Hidroklorida merupakan antagonis reseptor histamin H2 secara selektif dan reversible dengan waktu paruh yang pendek yaitu 2,5-3 jam, sehingga perlu dikembangkan sediaan lepas lambat dalam bentuk mucoadhesive.
Cahyani, R. H. (Revita)
core
Locust bean gum: exploring its potential for biopharmaceutical applications [PDF]
, 2012 Polysaccharides have been finding, in the last decades, very interesting and useful applications in the biomedical and, specifically, in the biopharmaceutical field.
Dionísio, Marita, Grenha, Ana
core +2 more sources
Differential efficacy of L- and T-type calcium channel blockers in preventing tachycardia-induced atrial remodeling in dogs [PDF]
, 2017 Background: Tachycardia-induced remodeling likely plays an important role in atrial fibrillation (AF) maintenance and recurrence after cardioversion, and Ca2+ overload may be an important mediator.
Bénardeau, Agnès +2 more
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Coronary and systemic hemodynamic effects of intravenous nisoldipine [PDF]
, 1986 Systemic and coronary hemodynamic effects of the new dihydropyridine calcium antagonist nisoldipine were studied over a 30-minute period in 12 patients with angina pectoris. Previously instituted beta-blocker therapy was continued.
Feyter, P.J. (Pim) de +3 more
core
A case of Diltiazem hydrochloride induced hepatitis
Kanzo, 1977 症例は64歳男性.抗Ca〓性冠循環増強剤Diltiazem hydrochloride (Herbesser)の二度目の服用後,全身掻痒感と黄疸,食欲不振が出現し,総コレステロール,中性脂肪,γ-GTPの著明な上昇とトランスアミナーゼの中等度上昇が認められた.また,同時に全身の発疹と一過性の好酸球増多がみられた.肝生検像は主に小葉中心帯に軽度の脂肪変性と肝細胞内胆汁うっ滞像,小巣壊死,グ鞘に軽度の単核細胞浸潤を認めた.本症は薬剤によるリンパ球刺激試験が陽性であった.
Kenichi IDO +5 more
openaire +2 more sources