Results 71 to 80 of about 5,295 (204)

Patterns of antihypertensive prescribing, discontinuation and switching among a Hong Kong Chinese population from over one million prescriptions [PDF]

, 2008
Hypertension is an alarming public health problem among Chinese. The present study evaluated the prescribing patterns, discontinuation and switching profiles of antihypertensive agents and their associated factors in one Hong Kong Chinese population ...
A Fretheim, A T Lam, BM Cheung, G Onder, H Fung, H Mori, J Ma, J Y Jiang, M C S Wong, MCS Wong, S Griffiths, S W Mercer, T Walley, YH Yuen, Z Kabir   +14 more
core   +1 more source

Neuron–non‐neuron electrical coupling networks are involved in chronic stress‐induced electrophysiological changes in lateral habenular neurons

The Journal of Physiology, Volume 603, Issue 9, Page 2713-2740, 1 May 2025.
Abstract figure legend We investigated electrophysiological changes in lateral habenula (LHb) neurons induced by chronic social defeat stress in mice. LHb neurons exhibited short (<400 ms) rebound depolarizing potentials (short‐RDPs) or long‐RDPs (order of seconds) (long‐RDPs) after the offset of hyperpolarization. The incidence of long‐RDP neurons was
Kenji Yamaoka, Kanako Nozaki, Meina Zhu, Haruhi Terai, Kenta Kobayashi, Hikaru Ito, Miho Matsumata, Hidenori Takemoto, Shinya Ikeda, Yusuke Sotomaru, Tetsuji Mori, Hidenori Aizawa, Kouichi Hashimoto   +12 more
wiley   +1 more source

Some variables affecting the characteristics of Eudragit E-sodium alginate polyelectrolyte complex as a tablet matrix for diltiazem hydrochloride

Acta Pharmaceutica, 2014
Eudragit E (EE)-sodium alginate (SA) polyelectrolyte complexes (PECs) were prepared at pH 4 and 5.8 using sodium alginate of high (SAH) and low viscosity (SAL).
Yusif Rehab Mohammad, Hashim Irhan Ibrahim Abu, El-Dahan Marwa Salah   +2 more
doaj   +1 more source

Small-Molecule Screen Identifies Reactive Oxygen Species as Key Regulators of Neutrophil Chemotaxis [PDF]

, 2014
Neutrophil chemotaxis plays an essential role in innate immunity, but the underlying cellular mechanism is still not fully characterized. Here, using a small-molecule functional screening, we identified NADPH oxidase–dependent reactive oxygen species as ...
Blanchard, Catlyn, Hattori, Hidenori, Jia, Yonghui, Jo, Hakryul, Kasorn, Anongnard, Li, Yitang, Loison, Fabien, Luo, Hongbo, McDonald, Douglas Ray, Pai, Sung-Yun, Porter, Timothy F., Sakai, Jiro, Sarraj, Bara, Serhan, Charles Nicholas, Subramanian, Kulandayan K., Zirkle, Dorothy   +15 more
core   +1 more source

Part 2: Drug Interactions Involving Cannabis Products in Persons Aged 18 and Over: A Summary of Published Case Reports and Analysis of the FDA Adverse Event Reporting System

Pharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT The increasing utilization of cannabis products combined with lack of data regarding potential cannabis–prescription drug interactions is concerning. This study aimed to review published case reports and FDA Adverse Event Reporting System (FAERS) spontaneous reports to assess cannabis–drug interactions in persons aged 18 and over. A literature
Maryann R. Chapin, Sandra L. Kane‐Gill, Xiaotong Li, Kojo Abanyie, Sanya B. Taneja, Susan Egbert, Mary F. Paine, Richard D. Boyce   +7 more
wiley   +1 more source

Association between chronic diseases and severe periodontal disease progression: A retrospective cohort study in a city of Japan

Journal of General and Family Medicine, Volume 26, Issue 1, Page 54-64, January 2025.
This manuscript is a study demonstrating the association between the progression of severe periodontal diseases and chronic diseases commonly addressed in primary care. We used claims data and defined the outcome as the “progression of severe periodontitis” and followed patients for 4 years.
Sayaka Nin, Yu Sun, Takami Maeno, Chihiro Nishiura, Kento Taira, Kenji Fujimoto, Jun Hamano, Sachiko Ozone, Tetsuhiro Maeno   +8 more
wiley   +1 more source

Evaluation of the Efficacy and Safety of Diltiazem and Lidocaine Combination Gel in the Treatment of Anal Fissures: A Prospective, Randomized, and Comparative Study

Indian Journal of Colo-Rectal Surgery
Background: Anal fissure is a common and painful anorectal condition affecting across all age groups. Pharmacological management remains the preferred first-line treatment due to its noninvasive nature and effectiveness in reducing pain, sphincter ...
Jaya Maheshwari
doaj   +1 more source

Differential behavioral state-dependence in the burst properties of CA3 and CA1 neurons [PDF]

, 2006
Brief bursts of fast high-frequency action potentials are a signature characteristic of CA3 and CA1 pyramidal neurons. Understanding the factors determining burst and single spiking is potentially significant for sensory representation, synaptic ...
Chrobak, J. J., Markus, E. J., Oler, J. A., Quirk, M. C., Tropp Sneider, J.   +4 more
core   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton, Michael R. Gionfriddo, Gail B. Rattinger, Yuan Fang, Mia E. Lussier   +4 more
wiley   +1 more source

Effects of simulated weightlessness on regional blood flow specifically during cardiovascular stress [PDF]

Significant changes in the cardiovasular system of humans and animals have been observed following exposure to prolonged periods of weightlessness during space flight.
Harrison, D. C.
core   +1 more source