Evaluations of the effect of sodium metabisulfite on the stability and dissolution rates of various model drugs from the extended release polyethylene oxide matrices [PDF]
, 2017 Purpose: This study examines the effect of sodium metabisulfite (SMB) as an antioxidant on the stability and release of various model drugs namely propranolol HCl, theophylline and zonisamide from the polyethylene oxide (PEO) tablets. The antioxidant was
Ali Nokhodchi +30 more
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Role of CA2+/calmodulin on ethanol neurobehavioral effects [PDF]
, 2014 Rationale. The cAMP-dependent protein kinase A (PKA) signaling transduction pathway has been shown to play an important role in the modulation of several ethanol-induced behaviors.
Baliño, Pablo +2 more
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Optimasi Tepung Lidah Buaya (Aloe Vera L.) Dan Carbopol 934p Sebagai Mucoadhesive Agent Pada Sediaan Mikrogranul Ranitidin Hcl Secara Simplex Lattice Design [PDF]
, 2017 Ranitidin Hidroklorida merupakan antagonis reseptor histamin H2 secara selektif dan reversible dengan waktu paruh yang pendek yaitu 2,5-3 jam, sehingga perlu dikembangkan sediaan lepas lambat dalam bentuk mucoadhesive.
Cahyani, R. H. (Revita)
core
A case of Diltiazem hydrochloride induced hepatitis
Kanzo, 1977 症例は64歳男性.抗Ca〓性冠循環増強剤Diltiazem hydrochloride (Herbesser)の二度目の服用後,全身掻痒感と黄疸,食欲不振が出現し,総コレステロール,中性脂肪,γ-GTPの著明な上昇とトランスアミナーゼの中等度上昇が認められた.また,同時に全身の発疹と一過性の好酸球増多がみられた.肝生検像は主に小葉中心帯に軽度の脂肪変性と肝細胞内胆汁うっ滞像,小巣壊死,グ鞘に軽度の単核細胞浸潤を認めた.本症は薬剤によるリンパ球刺激試験が陽性であった.
Kenichi IDO +5 more
openaire +2 more sources
Effects of verapamil on atrial fibrillation and its electrophysiological determinants in dogs [PDF]
, 2017 Background: Atrial tachycardia-induced remodeling promotes the occurrence and maintenance of atrial fibrillation (AF) and decreases L-type Ca2+ current. There is also a clinical suggestion that acute L-type Ca2 channel blockade can promote AF, consistent
Bénardeau, Agnès +2 more
core
, 2018 We compare two of the most successful models for the description and analysis of drug release data. The fractal kinetics approach leading to release profiles described by a Weibull function and the fractional kinetics approach leading to release profiles
Kosmidis, Kosmas, Macheras, Panos
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Drug Design, Development and Therapy, 2020 Afrasim Moin,1 Hosahalli V Gangadharappa,2 Mohd Adnan,3 Syed M Rizvi,1 Syed A Ashraf,4 Mitesh Patel,5 Amr S Abu Lila,1,6 Ahmed N Allam7 1Department of Pharmaceutics, College of Pharmacy, University of Hail, Hail, Saudi Arabia; 2Department of ...
Moin A +7 more
doaj
The Physical Compatibility of Clinically Used Concentrations of Diltiazem Hydrochloride With Heparin Sodium. [PDF]
J Pharm Technol, 2020 Dobson SR +3 more
europepmc +1 more source
Coronary and systemic hemodynamic effects of intravenous nisoldipine [PDF]
, 1986 Systemic and coronary hemodynamic effects of the new dihydropyridine calcium antagonist nisoldipine were studied over a 30-minute period in 12 patients with angina pectoris. Previously instituted beta-blocker therapy was continued.
Feyter, P.J. (Pim) de +3 more
core
The effect of pH and Polymer type on Release of Diltiazem HCl from hydrophilic matrices
Journal of Mazandaran University of Medical Sciences, 2007 Background and Purpose: Oral administrations have been used for many years as a main method comparing to other methods. Sustained release techniques have been a great interest recently.
J. Akbari, Ph.D. +3 more
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