Results 51 to 60 of about 1,859 (161)

Neuron–non‐neuron electrical coupling networks are involved in chronic stress‐induced electrophysiological changes in lateral habenular neurons

The Journal of Physiology, Volume 603, Issue 9, Page 2713-2740, 1 May 2025.
Abstract figure legend We investigated electrophysiological changes in lateral habenula (LHb) neurons induced by chronic social defeat stress in mice. LHb neurons exhibited short (<400 ms) rebound depolarizing potentials (short‐RDPs) or long‐RDPs (order of seconds) (long‐RDPs) after the offset of hyperpolarization. The incidence of long‐RDP neurons was
Kenji Yamaoka, Kanako Nozaki, Meina Zhu, Haruhi Terai, Kenta Kobayashi, Hikaru Ito, Miho Matsumata, Hidenori Takemoto, Shinya Ikeda, Yusuke Sotomaru, Tetsuji Mori, Hidenori Aizawa, Kouichi Hashimoto   +12 more
wiley   +1 more source

Evaluation of the Efficacy and Safety of Diltiazem and Lidocaine Combination Gel in the Treatment of Anal Fissures: A Prospective, Randomized, and Comparative Study

Indian Journal of Colo-Rectal Surgery
Background: Anal fissure is a common and painful anorectal condition affecting across all age groups. Pharmacological management remains the preferred first-line treatment due to its noninvasive nature and effectiveness in reducing pain, sphincter ...
Jaya Maheshwari
doaj   +1 more source

Part 2: Drug Interactions Involving Cannabis Products in Persons Aged 18 and Over: A Summary of Published Case Reports and Analysis of the FDA Adverse Event Reporting System

Pharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT The increasing utilization of cannabis products combined with lack of data regarding potential cannabis–prescription drug interactions is concerning. This study aimed to review published case reports and FDA Adverse Event Reporting System (FAERS) spontaneous reports to assess cannabis–drug interactions in persons aged 18 and over. A literature
Maryann R. Chapin, Sandra L. Kane‐Gill, Xiaotong Li, Kojo Abanyie, Sanya B. Taneja, Susan Egbert, Mary F. Paine, Richard D. Boyce   +7 more
wiley   +1 more source

Association between chronic diseases and severe periodontal disease progression: A retrospective cohort study in a city of Japan

Journal of General and Family Medicine, Volume 26, Issue 1, Page 54-64, January 2025.
This manuscript is a study demonstrating the association between the progression of severe periodontal diseases and chronic diseases commonly addressed in primary care. We used claims data and defined the outcome as the “progression of severe periodontitis” and followed patients for 4 years.
Sayaka Nin, Yu Sun, Takami Maeno, Chihiro Nishiura, Kento Taira, Kenji Fujimoto, Jun Hamano, Sachiko Ozone, Tetsuhiro Maeno   +8 more
wiley   +1 more source

Tools for clinical pharmacists to identify medications that can cause drug‐induced cognitive impairment: A systematic review

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 7, Issue 12, Page 1207-1227, December 2024.
Abstract Cognitive impairment affects around 19% of community‐dwelling older adults in the United States. Pharmacists can play a significant role in identifying and deprescribing cognitive‐impairing medications through cognitive‐focused medication reviews or as part of comprehensive medication management.
Jacob Stanton, Michael R. Gionfriddo, Gail B. Rattinger, Yuan Fang, Mia E. Lussier   +4 more
wiley   +1 more source

Permeability studies of Damar Batu free films for transdermal application [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2009
Damar Batu (DB) looks like stone with black or dark brown color inside. Due to its film forming ability it is used in the manufacture of paper, wood, varnishes, lacquers, polishes and additives for beverages. In the present study the permeability of free
ATISH S. MUNDADA, JASMINE G. AVARI
doaj  

Development of a new methodology for dissolving tablets containing diltiazem hydrochloride marketed in Brazil using design of experiment [PDF]

Brazilian Journal of Pharmaceutical Sciences
Diltiazem hydrochloride (DH) is a calcium channel blocker used to modify or restore normal heart rhythm in cardiovascular diseases. The aim of this study was to develop and validate a new innovative method using UV molecular absorption spectrophotometry ...
Laura Beatriz Souza e Souza, Ivana Ferreira Simões, Orlando Maia Barboza, Anderson Silva de Oliveira, Daniel Levi França da Silva, Walter Nei Lopes dos Santos, Aníbal de Freitas Santos Júnior   +6 more
doaj   +2 more sources

Evaluation of gum mastic (Pistacia lentiscus) as a microencapsulating and matrix forming material for sustained drug release

Asian Journal of Pharmaceutical Sciences, 2017
In this study, a natural gum mastic was evaluated as a microencapsulating and matrix-forming material for sustained drug release. Mastic was characterized for its physicochemical properties.
Dinesh M. Morkhade
doaj   +1 more source

Formulation and Evaluation of Chitosan-Gellan Beads as Controlled Drug Delivery System of Antihypertensive Drug

Journal of Basic and Applied Research in Biomedicine, 2022
The use of natural polymers in the design of drug delivery formulation has received much attention due to their excellent biocompatibility and biodegradability.
Rohit Bhosale, Riyaz Ali Osmani, H Gangadharappa   +2 more
doaj   +2 more sources

In vitro and in vivo investigation for optimization of niosomal ability for sustainment and bioavailability enhancement of diltiazem after nasal administration

Drug Delivery, 2017
Diltiazem hydrochloride (DTZ) is a calcium channel antagonist depicted by extensive first pass metabolism and low oral bioavailability. The aim of this work was to develop niosomes for potential nasal delivery of DTZ.
H. O. Ammar, M. Haider, M. Ibrahim, N. M. El Hoffy   +3 more
doaj   +1 more source