Results 51 to 60 of about 58,398 (178)

Formulation and evaluation of microspheres of diltiazem hydrochloride

Indian Journal of Pharmaceutical Sciences, 2007
Microspheres of diltiazem hydrochloride were formulated using combination of polyethylene glycol 6000 and Eudragit RS 100 and Eudragit RS 100 alone by solvent evaporation and non-solvent addition methods with an aim to prolong its release. Six formulations prepared by using different drug to polymer ratios, were evaluated for relevant parameters and ...
M Nappinnai, VS Kishore
openaire   +1 more source

Preparation and Characterization of Diltiazem Hydrochloride Matrix Tablets

, 2020
Developing oral controlled release tablets for highly water-soluble drugs with constant release rate has always been a challenge to the pharmaceutical technologist.
Mamatha Gt, Jayanthi C, Hanumanthachar Joshi, Ramesh, Sandeep A   +4 more
core  

Formulation of gastro-retentive floating tables of Diltiazem Hydrochloride wtih carnauba wax by melt granulation technique

, 2011
The study was carried out to investigate drug release profile of gastroretentive drug delivery system (GDDS) of diltiazem hydrochloride prepared with a hydrophilic polymer (hydroxylpropyl methyl cellulose), hydrophobic polymer (ethyl cellulose) and a ...
Latha, K, MV Srikanth, KV Ramana Murthy, Srikanth, MV, Ramana Murthy, KV, SA Sunil, K Latha, MU Uhumwangho, Sunil, SA, Uhumwangho, MU   +9 more
core   +1 more source

Permeability studies of Damar Batu free films for transdermal application [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2009
Damar Batu (DB) looks like stone with black or dark brown color inside. Due to its film forming ability it is used in the manufacture of paper, wood, varnishes, lacquers, polishes and additives for beverages. In the present study the permeability of free
ATISH S. MUNDADA, JASMINE G. AVARI
doaj  

Development of a new methodology for dissolving tablets containing diltiazem hydrochloride marketed in Brazil using design of experiment [PDF]

Brazilian Journal of Pharmaceutical Sciences
Diltiazem hydrochloride (DH) is a calcium channel blocker used to modify or restore normal heart rhythm in cardiovascular diseases. The aim of this study was to develop and validate a new innovative method using UV molecular absorption spectrophotometry ...
Laura Beatriz Souza e Souza, Ivana Ferreira Simões, Orlando Maia Barboza, Anderson Silva de Oliveira, Daniel Levi França da Silva, Walter Nei Lopes dos Santos, Aníbal de Freitas Santos Júnior   +6 more
doaj   +2 more sources

In vitro and in vivo investigation for optimization of niosomal ability for sustainment and bioavailability enhancement of diltiazem after nasal administration

Drug Delivery, 2017
Diltiazem hydrochloride (DTZ) is a calcium channel antagonist depicted by extensive first pass metabolism and low oral bioavailability. The aim of this work was to develop niosomes for potential nasal delivery of DTZ.
H. O. Ammar, M. Haider, M. Ibrahim, N. M. El Hoffy   +3 more
doaj   +1 more source

Evaluation of gum mastic (Pistacia lentiscus) as a microencapsulating and matrix forming material for sustained drug release

Asian Journal of Pharmaceutical Sciences, 2017
In this study, a natural gum mastic was evaluated as a microencapsulating and matrix-forming material for sustained drug release. Mastic was characterized for its physicochemical properties.
Dinesh M. Morkhade
doaj   +1 more source

Formulation and Evaluation of Chitosan-Gellan Beads as Controlled Drug Delivery System of Antihypertensive Drug

Journal of Basic and Applied Research in Biomedicine, 2022
The use of natural polymers in the design of drug delivery formulation has received much attention due to their excellent biocompatibility and biodegradability.
Rohit Bhosale, Riyaz Ali Osmani, H Gangadharappa   +2 more
doaj   +2 more sources

A time-released osmotic pump fabricated by compression-coated method: Formulation screen, mechanism research and pharmacokinetic study

Asian Journal of Pharmaceutical Sciences, 2014
In this investigation, time-released monolithic osmotic pump (TMOP) tablets containing diltiazem hydrochloride (DIL) were prepared on the basis of osmotic pumping mechanism.
Tiegang Xin, Yang Zhao, Hengpan Jing, Wenji Zhang, Yunyun Gao, Xinggang Yang, Xukai Qu, Weisan Pan   +7 more
doaj   +1 more source

A case of Diltiazem hydrochloride induced hepatitis

Kanzo, 1977
症例は64歳男性.抗Ca〓性冠循環増強剤Diltiazem hydrochloride (Herbesser)の二度目の服用後,全身掻痒感と黄疸,食欲不振が出現し,総コレステロール,中性脂肪,γ-GTPの著明な上昇とトランスアミナーゼの中等度上昇が認められた.また,同時に全身の発疹と一過性の好酸球増多がみられた.肝生検像は主に小葉中心帯に軽度の脂肪変性と肝細胞内胆汁うっ滞像,小巣壊死,グ鞘に軽度の単核細胞浸潤を認めた.本症は薬剤によるリンパ球刺激試験が陽性であった.
IDO, Kenichi, YOSHIDA, Yukio, TSUCHIYA, Masahisa, YAMANAKA, Takeo, KIMURA, Ken, MATSUMOTO, Saburo   +5 more
openaire   +2 more sources