Brazilian Journal of Pharmaceutical Sciences, 2011 Diltiazem hydrochloride is a calcium channel blocker generally indicated for the treatment of angina and hypertension, and it is extensively metabolized due to the hepatic metabolism.
Swati Changdeo Jagdale +3 more
doaj +1 more source
Increase in systolic blood pressure during exercise testing after heart transplantation: correlation with the clinical condition and ventricular function assessed by dobutamine stress echocardiography [PDF]
, 2006 OBJECTIVE: Patients who underwent heart transplantation (HTX) experience a reduction in the elevation that is usual in systolic blood pressure during exercise testing. Of unknown origin, this phenomenon varies in frequency and intensity.
Almeida, Dirceu Rodrigues de +7 more
core +4 more sources
Cellular Physiology and Biochemistry, 2014 Aims: Effect and mechanism of Yulangsan flavonoid (YLSF) on rat myocardial ischemia/reperfusion injury (MI/RI) has been investigated. Methods: Sprague-Dawley (SD) rats were randomly divided into seven groups (sham group, model group and NS group: 2 mL of
Xudong Zhang +9 more
doaj +1 more source
Toxicological and ecotoxicological risk‐based prioritization of pharmaceuticals in the natural environment [PDF]
, 2016 Approximately 1500 active pharmaceutical ingredients are currently in use; however, the environmental occurrence and impacts of only a small proportion of these have been investigated.
Agerstrand +37 more
core +1 more source
Wound, pressure ulcer, and burn guidelines (2023)-4: Guidelines for the management of connective tissue disease/vasculitis-associated skin ulcers, third edition. [PDF]
J DermatolThe Journal of Dermatology, Volume 52, Issue 6, Page e430-e480, June 2025.
Asano Y +27 more
europepmc +2 more sources
Formulation and In-Vitro Evaluation of Mucoadhesive Diltiazem Hydrochloride Buccal Tablets
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2011 Mucoadhesive tablets for buccal administration of diltiazem hydrochloride were prepared as an alternative to available diltiazem HCl dosage forms. Two types of tablets were developed each containing two mucoadhesive components (hydroxypropylmethyl ...
Lubna A. Sabri
doaj +1 more source
Diltiazem hydrochloride: New technologies and evolution of diltiazem [PDF]
Clinical Cardiology, 2009 Graded extended-release diltiazem (CARDIZEM® LA) (GRD) is a new formulation of diltiazem engineered to provide more precise blood pressure control than traditional antihypertensive agents. Unlike other diltiazem once-daily formulations, CARDIZEM® LA is a tablet formulation. Its pharmacokinetic profile differs from that of CARDIZEM® CD, another extended-
openaire +1 more source
In situ monitoring of powder blending by non-invasive Raman spectrometry with wide area illumination [PDF]
, 2013 A 785 nm diode laser and probe with a 6 mm spot size were used to obtain spectra of stationary powders and powders mixing at 50 rpm in a high shear convective blender.
Allan, Pamela +5 more
core +1 more source
The evaluation of Eudragit microcapsules manufactured by solvent evaporation using USP Apparatus 1 [PDF]
, 2009 The objectives of this study were to prepare microcapsules containing verapamil and propranolol and to evaluate the kinetics and mechanism of drug release from the microcapsules using USP Apparatus 1. The effects of polymer concentration and polymer type
Haidula, H +4 more
core +2 more sources
Frontiers in Cardiovascular Medicine, 2022 BackgroundThe adverse effects of anticancer therapy in patients with malignancies and cardiovascular diseases are complicated. Oxaliplatin is one of the most commonly used chemotherapy drugs for gastric and colorectal cancers, and oxaliplatin-induced ...
Xi Chen +6 more
doaj +1 more source