Results 31 to 40 of about 1,803 (117)

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Development and validation of a stability indicating HPLC method to determine diltiazem hydrochloride in tablets and compounded capsules

Brazilian Journal of Pharmaceutical Sciences, 2017
A stability indicating HPLC method to determine diltiazem hydrochloride (DTZ) in tablets and compounded capsules was developed and validated according to Brazilian and the International Conference on Harmonization (ICH) guidelines.
Mateus Araújo Castro e Souza, Carlos Eduardo de Oliveira Pereira, Fernando Henrique Andrade Nogueira, Gerson Antônio Pianetti   +3 more
doaj   +1 more source

Coronary arterial spasm detected by coronary computed tomography angiography and confirmed by intravascular ultrasound

Radiology Case Reports, 2018
A 40-year-old man was admitted to our hospital for chest pain after smoking. Coronary computed tomography angiography showed severe stenosis in the left anterior descending artery.
Masafumi Nakayama, MD, Masaharu Hirano, MD, Sonoka Goto, MD, Akifumi Watanabe, MD, Takashi Uchiyama, MD   +4 more
doaj   +1 more source

Aortic Stiffness in L-NAME Treated C57Bl/6 Mice Displays a Shift From Early Endothelial Dysfunction to Late-Term Vascular Smooth Muscle Cell Dysfunction

Frontiers in Physiology, 2022
Introduction and Aims: Endothelial dysfunction is recognized as a cardiovascular aging hallmark. Administration of nitric oxide synthase blocker N-Ω-Nitro-L-arginine methyl ester hydrochloride (L-NAME) constitutes a well-known small animal model of ...
Sofie De Moudt, Jhana O. Hendrickx, Cédric Neutel, Dorien De Munck, Arthur Leloup, Guido R.Y. De Meyer, Wim Martinet, Paul Fransen   +7 more
doaj   +1 more source

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu, James Duffy, Arnold Donkor Forkuo, Stephen Y. Gbedema, Seham Abdelall, Muhammad Wahajuddin, Huw S. Jones, Colin W. Wright   +7 more
wiley   +1 more source

Development of sustained-release floating tablets of diltiazem hydrochloride

Vietnam Journal of Science, Technology and Engineering
Diltiazem hydrochloride (DTZ), utilised for cardiovascular conditions, possesses a short half-life, necessitating frequent dosing. To enhance compliance, sustainedrelease (SR) floating tablets were developed using a Quality by Design (QbD) approach ...
Hung Pham Van, Tung Nguyen Thanh, Nhat Hoang Thi Anh, Hieu Bui Trung, Uyen Dinh Thi Thu, Duyen Nguyen Thi Thanh   +5 more
doaj   +3 more sources

Pharmacokinetics of diltiazem hydrochloride delay-onset sustained-release pellet capsules in healthy volunteers

Brazilian Journal of Pharmaceutical Sciences, 2013
The pharmacokinetics (PK) of ordinary tablets and sustained release capsules of diltiazem hydrochloride in human clinical trials had been studied. The PK of diltiazem hydrochloride delay-onset sustained-release pellet capsules, a new dosage form, has not
Xi-Qing Yan, Zhi-Gang Chen, Rong-Liang Wang, Jun Yang, Fang Ai, Yan-Juan Pan, Pei-Yong Qiu, Da-Xin Wang   +7 more
doaj  

Heart Failure: Epidemiology, Pathophysiology, and Management

MedComm, Volume 7, Issue 3, March 2026.
This article takes calcium homeostasis as the point of departure to provide an overview of heart failure from three perspectives—epidemiology, pathophysiological mechanisms, and management strategies—and summarizes the current unmet needs and future directions in the field. ABSTRACT Heart failure (HF) is one of the leading causes of hospitalization and
Yujian Fan, Zhihua Yang, Qing Li, Meng Sun, Yumeng Pu, Ke Zhao, Yu Bao, Xianliang Wang, Jingyuan Mao, Zhiqiang Zhao   +9 more
wiley   +1 more source

Critical insights into analytical methodologies for lidocaine hydrochloride and diltiazem hydrochloride: a comparative review

Future Journal of Pharmaceutical Sciences
Background This study focuses on a fixed-dose combination of lidocaine hydrochloride and diltiazem hydrochloride for the treatment of anal fissures, where lidocaine acts as an anesthetic and diltiazem serves as a slow calcium channel blocker.
Shivani Patel, Archita Patel, Chandni Chandarana, Bhavesh Patel, Mehul Patel, Umang Shah, Swayamprakash Patel, Nilay Solanki, Drashti Shah, Ashish Patel   +9 more
doaj   +1 more source

Anogenital Contact Dermatitis in Spain: A REIDAC Study of Patients Undergoing Patch Testing in 2019–2024

Contact Dermatitis, Volume 94, Issue 3, Page 272-285, March 2026.
Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez, Pedro Mercader‐García, Ana María Giménez‐Arnau, Tatiana Sanz‐Sánchez, Violeta Zaragoza Ninet, Susana Córdoba Guijarro, Francisco Javier Miquel Miquel, Juan Francisco Silvestre Salvador, Ricardo González‐Pérez, Inmaculada Ruíz González, Esther Serra Baldrich, José Manuel Carrascosa, Francisco Javier Ortiz de Frutos, Mercedes Rodríguez Serna, María Elena Gatica Ortega, Carmen Paredes Suárez, Francisco José Navarro Triviño, Pablo Chicharro, Marta Andreu, Araceli Sánchez Gilo, José Juan Pereyra Rodríguez, María Antonia Pastor Nieto, Gemma Melé‐Ninot, Paloma Sánchez‐Pedreño Guillén, Enrique Gómez de la Fuente, Marta Elosua‐González, Mónica Munera‐Campos, Fátima Tous Romero, Miguel Ángel Descalzo, Leopoldo Borrego   +29 more
wiley   +1 more source