Results 31 to 40 of about 58,398 (178)
Herbal carrier-based floating microparticles of diltiazem hydrochloride for improved cardiac activity [PDF]
Purpose: To formulate and characterize a gastroretentive floating drug delivery system for diltiazem hydrochloride using psyllium husk and sodium alginate as natural herbal carriers to improve the therapeutic effect of the drug in cardiac patients ...
Zhao, Xin-Fang +6 more
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Diltiazem hydrochloride: New technologies and evolution of diltiazem [PDF]
Graded extended-release diltiazem (CARDIZEM® LA) (GRD) is a new formulation of diltiazem engineered to provide more precise blood pressure control than traditional antihypertensive agents. Unlike other diltiazem once-daily formulations, CARDIZEM® LA is a tablet formulation. Its pharmacokinetic profile differs from that of CARDIZEM® CD, another extended-
openaire +1 more source
Formulation and In-Vitro Evaluation of Mucoadhesive Diltiazem Hydrochloride Buccal Tablets
Mucoadhesive tablets for buccal administration of diltiazem hydrochloride were prepared as an alternative to available diltiazem HCl dosage forms. Two types of tablets were developed each containing two mucoadhesive components (hydroxypropylmethyl ...
Lubna A. Sabri
doaj +1 more source
Orodispersible film (ODF) is a better alternate to oral disintegrating tablets owing to its ease in application and subsequent patient compliance. This study investigates an improvement in physico-mechanical properties and palatability of Diltiazem ...
Sumera Latif +9 more
doaj +1 more source
Preparation and Dissolution Characteristics of Sustained Release Diltiazem Hydrochloride Tablets
In the present study, the applicability of Eudragit to produce matrix tablet by a wet granulation technique was evaluated. The effect of various formulation variables on the release of drug from these tablets was examined.
Kohli, K +7 more
core +1 more source
OPTIMIZATION OF THE RELEASE KINETICS OF DILTIAZEM HYDROCHLORIDE FROM TABLETED MICROSPHERES
Formulation F5, F6, F7 and F8 were selected to make the tablets because of their high percentage release (more than 90%). 500 mg weight of tablets containing 120 mg strength of Diltiazem hydrochloride were prepared from formulations F5, F6, F7 and F8. ...
Khunteta, Alok +3 more
core +1 more source
Formulation and Optimization of Gastric Bioadhesive Tablets of Diltiazem Hydrochloride using Central Composite Design [PDF]
Purpose: To develop bioadhesive tablets of diltiazem hydrochloride with a unique combination of bioadhesion and drug release. Method: Tablets were prepared by physical blending of diltiazem hydrochloride with two polymers, viz., carbopol and ...
Sharma, Saurabh +2 more
core +4 more sources
BackgroundThe adverse effects of anticancer therapy in patients with malignancies and cardiovascular diseases are complicated. Oxaliplatin is one of the most commonly used chemotherapy drugs for gastric and colorectal cancers, and oxaliplatin-induced ...
Xi Chen +6 more
doaj +1 more source
The study was designed to formulate and evaluate diltiazem hydrochloride wax matrix tablets for controlled release using sintering technique. Granules of diltiazem hydrochloride-wax were prepared by melt granulation technique.
Ramana Murthy, KV, Uhumwangho, MU
core +1 more source
Release Characteristics of Diltiazem Hydrochloride Wax-Matrix Granules – Thermal Sintering Effect [PDF]
The aim of this study was to investigate the release characteristics of matrix (non-disintegrating) granules consisting of diltiazem hydrochloride (model drug) and glyceryl behenate (a wax matrix forming polymer) for sustained release application using ...
MURTHY, K V RAMANA, UHUMWANGHO, M U
core +2 more sources

