Results 21 to 30 of about 58,398 (178)

Highly stretchable gelatin‐polyacrylamide hydrogel for potential transdermal drug release

open access: yesNano Select, 2021
Stretchable hydrogels have been used for a number of biomedical applications. This research focused on the study of a highly stretchable and tough hydrogel made of gelatin and polyacrylamide towards transdermal drug delivery applications.
Zhen Qiao   +6 more
doaj   +1 more source

A novel stability-indicating method for known and unknown impurities profiling for diltiazem hydrochloride pharmaceutical dosage form (tablets)

open access: yesFuture Journal of Pharmaceutical Sciences, 2021
Background A novel gradient, high-sensitive and specific stability-indicating reverse-phase HPLC method was developed and validated for quantitative purpose of known, unknown and degradant impurities profiling for diltiazem hydrochloride tablets.
Nitin Mahajan   +2 more
doaj   +1 more source

An Expired Non-Toxic Diltiazem Hydrochloride as Corrosion Inhibitor for Cu in Nitric Acid Medium

open access: yesInternational Journal of Electrochemical Science, 2017
The corrosion inhibition of Cu in 1 M HNO3 solution by expired Diltiazem Hydrochloride (HD) has been tested by Tafel polarization, electrical frequency modulation, electrical impedance spectroscopy, and mass loss method. The Diltiazem Hydrochloride gives
A.S. Fouda   +3 more
doaj   +1 more source

In vitro and ex vivo studies on Diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment [PDF]

open access: yes, 2019
Diltiazem hydrochloride, topically applied at 2% concentration, is considered effective for the treatment of chronic anal fissures, although it involves several side effects among which anal pruritus and postural hypotension.
Filomena Corbo   +21 more
core   +1 more source

PREFORMULATION STUDIES OF DILTIAZEM HYDROCHLORIDE FROM TABLETED MICROSPHERES [PDF]

open access: yes, 2018
Microspheres are solid, spherical particles of protein or polymer-based matrix which comprised of a fairly homogeneous mixture of polymer and active agents.It undergoes considerable presystemic metabolism (45-55%) which results in reduced bioavailability.
Surendra Kumar Swarnkar   +3 more
core   +1 more source

Development of a Halothane-Adrenaline Arrhythmia Model Using In Vivo Guinea Pigs

open access: yesJournal of Pharmacological Sciences, 2004
In vivo antiarrhythmic effects of diltiazem hydrochloride and nifekalant hydrochloride, a pure class III antiarrhythmic drug (Vaughan Williams’ classification), on adrenaline induced ventricular arrhythmias were examined in halothane anesthetized guinea ...
Yoshiaki Noda, Keitaro Hashimoto
doaj   +1 more source

Lityum klorür ve diltiazemin sıçanlarda bazı davranış parametrelerine ve serum sodyum, potasyum, kalsiyum düzeylerine etkileri

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
İn this study we investigated the effects of diltiazem alone or in combination with lithium on some behavioral param eters and serum sodium potassium and calcium levels in rats. 36 W istar Albino rats were divided into 4 groups and treated as follows, C
Göksel Şener   +2 more
doaj  

FORMULATION AND EVALUATION OF FLOATING ORAL IN SITU GEL OF DILTIAZEM HYDROCHLORIDE [PDF]

open access: yes, 2016
Objective: The objective of the present study was to formulate and evaluate the floating in-situ gelling system of diltiazem hydrochloride.Methods: Sodium alginate based diltiazem hydrochloride floating in situ gelling systems were prepared by dissolving
Angel, P.   +4 more
core   +2 more sources

Mechanism of the Protective Effect of Yulangsan Flavonoid on Myocardial Ischemia/Reperfusion Injury in Rats

open access: yesCellular Physiology and Biochemistry, 2014
Aims: Effect and mechanism of Yulangsan flavonoid (YLSF) on rat myocardial ischemia/reperfusion injury (MI/RI) has been investigated. Methods: Sprague-Dawley (SD) rats were randomly divided into seven groups (sham group, model group and NS group: 2 mL of
Xudong Zhang   +9 more
doaj   +1 more source

Diltiazem hydrochloride with first order modified release

open access: yes, 2022
Diltiazem is a benzodiazepine derivative that actively blocks voltage-gated calcium channels in smooth muscle and the myocardium. Diltiazem hydrochloride was first approved by the FDA in 1982.
Kristín Káradóttir 1995-   +3 more
core   +1 more source

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