Results 81 to 90 of about 1,450,380 (307)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Data-driven vs. psychological personality temperaments: theoretical and clinical utility of personality measures in psychiatry

Frontiers in Psychiatry
Decades of research on personality identified dissociable psychological temperaments. Cloninger’s temperament and character theory used a psychobiological approach to differentiate three major dimensions of personality: harm avoidance, novelty seeking ...
Abdelrahman S. Sawalma, Abdelrahman S. Sawalma, Abdelrahman S. Sawalma, Mahmud A. Sehwail, Jürgen Dammers, Jürgen Dammers, Mohammad M. Herzallah, Mohammad M. Herzallah   +7 more
doaj   +1 more source

The role of dimensions in classification under predicates predicts their status in degree constructions

Glossa, 2017
This paper presents an experimental study of multidimensional gradability across categories. The study tests whether and to what extent the naturalness of multidimensional adjectives and nouns in degree constructions is predictable from their conceptual ...
Galit Weidman Sassoon, Julie Fadlon
doaj   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Surreal dimensions

Advances in Applied Mathematics, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ted Chinburg, Alexandra Ovetsky
openaire   +2 more sources

Comparison of correlation dimension and fractal dimension in estimating level of consciousness

, 2009
This paper compares the correlation dimension (D2) ,Higuchi fractal dimension (HFD),Katz fractal dimension(KFD)and Sevcik fractal dimension(SFD) approaches in estimating Depth of Anesthesia (DOA) based on of electroencephalogram (EEG). The single-channel
Zaghari, Bahareh
core  

Mechanochemical ammonia synthesis enhanced by silicon nitride as a defect-inducing physical promoter

Nature Communications
By enabling ammonia synthesis under near ambient conditions, mechanochemistry provides a paradigm shift, a new decentralized production method that avoids the high temperature (above 400 °C) and high pressure (above 200 bar) requirements of the ...
Jae Seong Lee, Sooyeon Kim, Seung-Hyeon Kim, Jae-Hoon Baek, Jeong-Min Seo, Se Jung Lee, Changqing Li, Runnan Guan, Boo-Jae Jang, Gao-Feng Han, Sang Soo Han, Jong-Beom Baek   +11 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source