Results 111 to 120 of about 4,393,923 (290)

LDR: A Package for Likelihood-Based Sufficient Dimension Reduction

Journal of Statistical Software, 2011
We introduce a new mlab software package that implements several recently proposed likelihood-based methods for sufficient dimension reduction. Current capabilities include estimation of reduced subspaces with a fixed dimension d, as well as estimation ...
R. Dennis Cook, Liliana M. Forzani, Diego R. Tomassi   +2 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Comparisons on different sEMG-features with Dimension-reduction methods in Hand Motion Recognition

, 2016
Hand motion recognition based on surface electromyography (sEMG) has drawn much attention over last decades. Generally, sEMG can be non-invasively measured on the skin, and then different stable features directly relating to hand motion are extracted ...
Zhao XG(赵新刚), Liu GJ(刘光军), Li ZY(李自由), Han JD(韩建达)   +3 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Research on manufacturing text classification based on improved genetic algorithm

Brazilian Archives of Biology and Technology
According to the features of texts, a text classification model is proposed. Base on this model, an optimized objective function is designed by utilizing the occurrence frequency of each feature in each category.
Zhou Kaijun, Tong Yifei
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Parsimonious Tensor Dimension Reduction

Journal of Computational and Graphical Statistics
Tensor data is emerging in many scientific applications, such as multi-tissue transcriptomics. In such cases, the covariates for each individual are no longer a vector. To apply traditional vector-based methods to this type of data, we need to either do the vectorization or analyze data marginally, which suffers a significant information loss.
Xin Xing, Peng Zeng, Youhui Ye, Wenxuan Zhong   +3 more
openaire   +2 more sources

A note on the choice of the number of slices in sliced inverse regression [PDF]

Sliced inverse regression (SIR) is a clever technique for reducing the dimension of the predictor in regression problems, thus avoiding the curse of dimensionality. There exist many contributions on various aspects of the performance of SIR.
Gather, Ursula, Becker, Claudia
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source