Results 41 to 50 of about 302,652 (280)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Chain-Splitting-Solving-Splicing Approach to Large-Scale OFISP-Modeled Satellite Range Scheduling Problem

IEEE Access
The dimension of the operational-fixed-interval-scheduling-problem-modeled (OFISP-modeled) $\mathcal {NP}$ -hard satellite range scheduling problem (SRSP) extends rather than expands especially in large cases.
De Meng, Zhen-Bao Liu, Yu-Hang Gao, Zu-Ren Feng, Wen-Hua Guo, Zhi-Gang Ren   +5 more
doaj   +1 more source

Structure Aware Generative Adversarial Networks for Hyperspectral Image Classification

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
Generative adversarial networks (GANs) have shown striking performances in computer vision applications to augment virtual training samples (VTS). However, the VTS generating by GANs in the context of hyperspectral image classification suffer from ...
Tayeb Alipour-Fard, Hossein Arefi
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

High‐performance computing of 3D blasting wave propagation in underground rock cavern by using 4D‐LSM on TianHe‐3 prototype E class supercomputer

Deep Underground Science and Engineering, 2022
Parallel computing assigns the computing model to different processors on different devices and implements it simultaneously. Accordingly, it has broad applications in the numerical simulation of geotechnical engineering and underground engineering, of ...
Meng Fu, Gaofeng Zhao
doaj   +1 more source

Growing Regression Forests by Classification: Applications to Object Pose Estimation

, 2014
In this work, we propose a novel node splitting method for regression trees and incorporate it into the regression forest framework. Unlike traditional binary splitting, where the splitting rule is selected from a predefined set of binary splitting rules
Chellappa, Rama, Hara, Kota
core   +1 more source

Multi-Leg One-Loop Gravity Amplitudes from Gauge Theory [PDF]

, 1998
By exploiting relations between gravity and gauge theories, we present two infinite sequences of one-loop n-graviton scattering amplitudes: the `maximally helicity-violating' amplitudes in N=8 supergravity, and the `all-plus' helicity amplitudes in ...
't Hooft, 't Hooft, Bardeen, Berends, Berends, Berends, Berends, Berends, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bern, Bershadsky, Bershadsky, Brown, Cangemi, Cangemi, Capper, Chalmers, Cutkosky, De Causmaecker, De Causmaecker, DeWitt, Dixon, Dixon, Donaldson, Duff, Duff, Dunbar, Dunbar, Gates, Gervais, Green, Green, Grisaru, Grisaru, Grisaru, Gubser, Gubser, Gunion, Horowitz, Howe, Howe, Howe, Howe, J.S. Rozowsky, Kachru, Kallosh, Kawai, Kleiss, Kleiss, Kosower, Kosower, Kunszt, Kunszt, L. Dixon, Landau, Lawrence, Leznov, Leznov, M. Perelstein, Mahlon, Mahlon, Maldacena, Mandelstam, Mandelstam, Mangano, Mangano, Marcus, Nair, Nair, Parke, Parke, Parkes, Passarino, Paton, Plebański, Plebánski, Rosly, Sannan, Siegel, Siegel, Siegel, van Neerven, Veltman, Weinberg, Weinberg, Witten, Xu, Yang, Z. Bern   +109 more
core   +5 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Study on the mechanical properties and failure mechanism of a multi-lithologic layered rock mass

Heliyon
The mechanical properties of multi-lithologic reservoir rock masses are complex, and the failure mechanism is not clear. This research belongs to the field of oil and gas exploration and development.
Bo Zeng, Guozhou Qiu, Haoyong Huang, Yintong Guo, Ersi Xu, Junchuan Gui, Junfeng Li   +6 more
doaj   +1 more source

Efficient implementation of geometric integrators for separable Hamiltonian problems

, 2013
We here investigate the efficient implementation of the energy-conserving methods named Hamiltonian Boundary Value Methods (HBVMs) recently introduced for the numerical solution of Hamiltonian problems.
Brugnano, Luigi, Caccia, Gianluca Frasca, Iavernaro, Felice   +2 more
core   +1 more source