Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Using Sensorized Gloves and Dimensional Reduction for Hand Function Assessment of Patients with Osteoarthritis. [PDF]
Gracia-Ibáñez V +5 more
europepmc +1 more source
An algorithm of moving pieces to become black alternation with white based on dimension reduction
Sha Yanfei +3 more
openalex +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Dimensional reduction by geometrical frustration in a cubic antiferromagnet composed of tetrahedral clusters. [PDF]
Okuma R +12 more
europepmc +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Models with radiative symmetry breaking typically feature strongly supercooled first-order phase transitions, which result in an observable stochastic gravitational wave background.
Maciej Kierkla +3 more
doaj +1 more source
Dimensional reduction of phenotypes from 53 000 mouse models reveals a diverse landscape of gene function. [PDF]
Konopka T, Vestito L, Smedley D.
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Dimensional reduction and incommensurate dynamic correlations in the S = 1 2 triangular-lattice antiferromagnet Ca<sub>3</sub>ReO<sub>5</sub>Cl<sub>2</sub>. [PDF]
Zvyagin SA +9 more
europepmc +1 more source

