Results 71 to 80 of about 22,548 (306)
Dynamic LTE network dimensioning - [PDF]
, 2014 Thesis. M.E. American University of Beirut. Department of Electrical and Computer Engineering, 2014. ET:6042Advisor : Dr. Zaher Dawy, Associate Professor , Electrical and Computer Engineering ; Members of Committee: Dr.
Jaber, Mona Tarek,
core
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 2016 Vectorl design of objects (CAD3D) indicates its dimensions according to standards previous to existence of the CAD3D systems. In many cases, it does not meet the needs of new Information and Communication Technologies (ICT), causing the repetition of ...
Felix Sanz-Adan [0000-0003-0532-7072] +3 more
core
Exploring challenges in dimensioning safety buffers : an empirical study
, 2023 Purpose The purposes of this study were (1) to explore empirical challenges in dimensioning safety buffers and their implications and (2) to organise those challenges into a framework.
Mattsson, Stig-Arne +5 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
EchoGéoThe new high-rise buildings planned in Europe since the 2000s crystallize the metropolization of territorial planning and the imaginary of the future.
Geoffrey Mollé
doaj +1 more source
Broad Multi-Parameter Dimensioning of Magnetocaloric Systems Using Statistical Learning Classifiers
Frontiers in Energy Research, 2020 Prototyping innovative energy devices is a complex multivariable dimensioning problem. For the case of magnetocaloric systems, one aims to obtain an optimized balance between energy conversion performance, useful power generated, and power consumed.
Daniel J. Silva +2 more
doaj +1 more source