Results 81 to 90 of about 22,548 (306)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Radio Access Network Dimensioning for 3G UMTS
, 2009 This thesis investigates the dimensioning of the UMTS Radio Access Network with specific focus on the Iub interface, which connects the Node B and the RNC.
Li, Xi
core
OpenFlow-based Link Dimensioning [PDF]
, 2014 In this demo we will demonstrate the possibility of using OpenFlow traffic measurements for link dimensioning purposes. Our solution runs on top of the Ryu OpenFlow controller and retrieves per-flow statistics metered at the OpenFlow switch.
de Oliveira Schmidt, R. +3 more
core
Dimensioning Methodology for OFDMA Networks
, 2009 In this paper, we present a comprehensive methodology to dimension an OFDMA (Orthogonal Frequency Division Multiple Access) network. We divide the dimensioning task into sub-blocks and present implementation details of each block. The first block has the
Baynat, Bruno +5 more
core +2 more sources
Advances in Applied Mathematics, 2002 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ted Chinburg, Alexandra Ovetsky
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2006 The complete geometrical tolerancing reference, from principles through to inspection, for all engineers designing components to the latest standards.Includes bibliographical references and index.Print version record.Cover; Geometrical Dimensioning and ...
Henzold, G.Handbook of geometrical tolerancing. +1 more
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Resource dimensioning through buffer sampling [PDF]
, 2006 Link dimensioning, i.e., selecting a (minimal) link capacity such that the ...
Mandjes, Michel +5 more
core