Results 81 to 90 of about 63,869 (278)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Design of roundabout in Horsens (Denmark) and comparison of Danish and Czech approach to design [PDF]

open access: yes, 2012
Cílem této bakalářské práce je návrh okružní křižovatky v Dánsku ve spolupráci s dánskou univerzitou VIA University College v Horsens a porovnání různých přístupů k řešení jednotlivých prvků okružních křižovatek v České republice a Dánsku.
Pěknica, Martin
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Broad Multi-Parameter Dimensioning of Magnetocaloric Systems Using Statistical Learning Classifiers

open access: yesFrontiers in Energy Research, 2020
Prototyping innovative energy devices is a complex multivariable dimensioning problem. For the case of magnetocaloric systems, one aims to obtain an optimized balance between energy conversion performance, useful power generated, and power consumed.
Daniel J. Silva   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RESOURCE ELEMENT-LEVEL DIMENSIONING OF LONG TERM EVOLUTION NETWORKS

open access: yesJournal of ICT, 2013
Long Term Evolution (LTE) of Universal Mobile Telecommunications System (UMTS) is the latest cellular technology coined by the third Generation Partnership Project (3GPP) and is currently being deployed worldwide.
Arshed Oudah
doaj  

Access Node Dimensioning for IPTV Traffic Using Effective Bandwidth

open access: yesCommunications, 2012
This article presents a dimensioning of capacity of access node (Black Diamond 12 804R) for IPTV source (6 channels of IPTV), which was one part of our project with Slovak Telecom.
Juraj Smiesko, Jana Uramova
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Konsol İstinat Duvarlarında Yükseklik Maliyet İlişkisinin Parçacık Sürü Algoritması İle İncelenmesi

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2020
Mühendislik yapılarının boyutlandırılması ile ilgili problemlerde, optimizasyon algoritmalarının kullanımına olan ilgi, son yıllarda hızlı bir artış göstermektedir.
Kemal Saplıoğlu, Soner Uzundurukan
doaj  

Flood lamination strategy based on a three-flood-diversion-area system management [PDF]

open access: yes, 2012
The flood lamination has for principal objective to maintain a downstream flow at a fixed lamination level. For this goal, it is necessary to proceed to the dimensioning of the river system capacity and to make sure of its management by taking into ...
Charbonnaud, Philippe   +6 more
core   +1 more source

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