Results 91 to 100 of about 22,548 (306)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Network calculus based dimensioning for industrial wireless mesh networks
, 2012 Wireless Mesh network is widely adopted in both wideband mobile communication network and short distance RF industrial network. As for the latter field, network robustness and real-time are two important issues. Network dimensioning is therefore required
Cui SJ(崔世界) +2 more
core
Civil and Environmental Engineering, 2018 The initial part of the paper briefly characterizes the present state of the track substructure dimensioning for the non-traffic load and the necessity of updating the design map of frost indexes IFd as a basis for dimensioning. A substantial part of the
Ižvolt Libor, Dobeš Peter, Pieš Juraj
doaj +1 more source
Fair and efficient network dimensioning with the reference point methodology
Journal of Telecommunications and Information Technology, 2006 The dimensioning of telecommunication networks that carry elastic traffic requires the fulfillment of two conflicting goals: maximizing the total network throughput and providing fairness to all flows.
Włodzimierz Ogryczak +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
RESOURCE ELEMENT-LEVEL DIMENSIONING OF LONG TERM EVOLUTION NETWORKS
Journal of ICT, 2013 Long Term Evolution (LTE) of Universal Mobile Telecommunications System (UMTS) is the latest cellular technology coined by the third Generation Partnership Project (3GPP) and is currently being deployed worldwide.
Arshed Oudah
doaj
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
The Many Dimensions of Dimension
, 2004 Some aspects of the history and impact of the dimension revolution are briefly surveyed, starting with Nordstrom's D=5 scalar gravity-electromagnetism unification.
openaire +2 more sources
Journal of Complexity, 2010 The authors address the problem of integration over the \(d\)-dimensional unit cube of a function \(f\) of \(d\) variables, \[ I_d(f) = \int_{[0,1]^d} f({\mathbf{x}}) d{\mathbf{x}}. \] It is possible to design an algorithm for which the error is bounded polynomially in \(d\), or independently of \(d\) under suitable conditions on the weighted function ...
Frances Y. Kuo +3 more
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source