Results 91 to 100 of about 246,439 (294)

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang   +9 more
wiley   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras   +19 more
wiley   +1 more source

Achieving Stable Paired Electrolysis of Captured CO2 and 5‐Hydroxymethylfurfural (HMF) via Tuning Anolyte Composition and Anode Surface

open access: yesAdvanced Functional Materials, EarlyView.
Highly stable paired electrolysis of CO2 and biomass‐derived alcohol (HMF) is achieved by replacing conventional alkaline electrolytes with a tailored triethylamine‐carbonate buffer and anion‐conducting ionomer coatings. This configuration effectively mitigates electrolyte degradation and pH instability typically encountered in alkaline CO2 ...
Mi‐Young Lee   +3 more
wiley   +1 more source

The Reaction of Benzylic Alcohols with Dimethyl Sulfoxide-Polyphosphoric Acid [PDF]

open access: bronze, 1968
Takeo Sato   +4 more
openalex   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

open access: yesAdvanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen   +9 more
wiley   +1 more source

Understanding Postdeposition Treatments of Hole‐Transporting Self‐Assembling Molecules for Perovskite/Silicon Tandem Solar Cells

open access: yesAdvanced Functional Materials, EarlyView.
The influence of postdeposition treatments on the formation of self‐assembling (mono)layers commonly utilized as hole transport layers in perovskite‐based solar cells is thoroughly investigated. The implementation of a washing step and an annealing step at temperatures exceeding the current literature standards leads to an enhanced layer quality and ...
Jann B. Landgraf   +14 more
wiley   +1 more source

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

open access: yesAdvanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue   +3 more
wiley   +1 more source

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