Local environment modulates whole-transcriptome expression in the seagrass Posidonia oceanica under warming and nutrients excess [PDF]
, 2022 The intensification of anomalous events of seawater warming and the co-occurrence with local anthropogenic stressors are threatening coastal marine habitats, including seagrasses, which form extensive underwater meadows.
Ambrosino, L. +6 more
core +1 more source
Modes of hydrocarbon oil biosynthesis revealed by comparative gene expression analysis for race A and race B strains of Botryococcus braunii [PDF]
, 2012 To clarify the oil biosynthetic routes of the oil-producing green alga Botryococcus braunii, here the race-specific gene expression patterns were examined using representative strains of race A and race B producing fatty acid- and triterpene-derived ...
Baba Masato +10 more
core +1 more source
Mapping condition-dependent regulation of metabolism in yeast through genome-scale modeling [PDF]
, 2013 Background: The genome-scale metabolic model of Saccharomyces cerevisiae, first presented in 2003, was the first genome-scale network reconstruction for a eukaryotic organism.
Bordel, Sergio +3 more
core +1 more source
Valproate induces the unfolded protein response by increasing ceramide levels [PDF]
, 2016 Bipolar disorder (BD), which is characterized by depression and mania, affects 1–2% of the world population. Current treatments are effective in only 40–60% of cases and cause severe side effects.
Cottier, Stéphanie +5 more
core +1 more source
Transcriptome analysis of the pulp of citrus fruitlets suggests that domestication enhanced growth processes and reduced chemical defenses increasing palatability [PDF]
, 2022 To identify key traits brought about by citrus domestication, we have analyzed the transcriptomes of the pulp of developing fruitlets of inedible wild Ichang papeda (Citrus ichangensis), acidic Sun Chu Sha Kat mandarin (C. reticulata) and three palatable
Borredá, Carles +3 more
core +1 more source
Network design and analysis for multi-enzyme biocatalysis [PDF]
, 2020 In vitro synthesis is a biotechnological alternative to classic chemical catalysts. However, the manual design of multi-step biosynthesis routes is very challenging, especially when enzymes from different organisms are involved.
Schuh, Lisa Katharina
core +1 more source
Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease [PDF]
, 2012 Background Systems biology holds promise as a new approach to drug target identification and drug discovery against neglected tropical diseases. Genome-scale metabolic reconstructions, assembled from annotated genomes and a vast array of bioinformatics ...
Blazier, Anna S +5 more
core +3 more sources
Impact of biospecimens handling on biomarker research in breast cancer [PDF]
, 2009 Background Gene expression profiling is moving from the research setting to the practical clinical use. Gene signatures able to correctly identify high risk breast cancer patients as well as to predict response to treatment are currently under intense ...
Loris De Cecco +8 more
core +1 more source
Mutation Rate and Gene Expression in Genetic Admixtures of Domesticated Citrus [PDF]
, 2023 Tesis por compendio[ES] La domesticación de los cítricos es un proceso en gran parte desconocido. Las investigaciones llevadas a cabo hasta la fecha indican que las variedades de cítricos que se comercializan en la actualidad son, en general, el producto
Pérez Román, Estela
core +1 more source
Phlebia radiata as an ethanol producing fungus : conversion of lignocelluloses and metabolic regulation under hypoxia [PDF]
, 2020 White rot Basidiomycota can decompose all wood components in nature and are therefore essential in recycling carbon in our forests and ecosystems. These fungi are filamentous organisms that reside on top of trunks and elongate their hyphae inside wood ...
Mattila, Hans
core